eF-site ID 1qz2-B
PDB Code 1qz2
Chain B

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Title Crystal Structure of FKBP52 C-terminal Domain complex with the C-terminal peptide MEEVD of Hsp90
Classification ISOMERASE/CHAPERONE
Compound FK506-binding protein 4
Source Homo sapiens (Human) (HS90B_HUMAN)
Sequence B:  GSHMEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD
KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVY
LKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWE
MNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL
EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIE
SCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVL
QLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE
EENKA
Description


Functional site

1) chain B
residue 221
type MOD_RES
sequence L
description Phosphotyrosine => ECO:0007744|PubMed:23186163
source Swiss-Prot : SWS_FT_FI1

2) chain B
residue 283
type MOD_RES
sequence E
description N6-acetyllysine => ECO:0007744|PubMed:19608861
source Swiss-Prot : SWS_FT_FI2

3) chain B
residue 374
type MOD_RES
sequence A
description Omega-N-methylarginine => ECO:0000250|UniProtKB:P30416
source Swiss-Prot : SWS_FT_FI3


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