eF-site ID 1qy8-A PDB Code 1qy8 Chain A click to enlarge Title Crystal Structure of the N-domain of the ER Hsp90 chaperone GRP94 in complex with Radicicol Classification CHAPERONE Compound Endoplasmin Source Canis familiaris (Dog) (Canis lupus familiaris) (ENPL_CANFA) Sequence A:  KSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDA LDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTG VGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSEL IGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFS VIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKY SQFINFPIYVWSSKTKTVWDWELMN Description Functional site 1) chain A residue 107 type sequence N description BINDING SITE FOR RESIDUE RDI A 338 source : AC1 2) chain A residue 110 type sequence D description BINDING SITE FOR RESIDUE RDI A 338 source : AC1 3) chain A residue 111 type sequence A description BINDING SITE FOR RESIDUE RDI A 338 source : AC1 4) chain A residue 114 type sequence K description BINDING SITE FOR RESIDUE RDI A 338 source : AC1 5) chain A residue 149 type sequence D description BINDING SITE FOR RESIDUE RDI A 338 source : AC1 6) chain A residue 154 type sequence M description BINDING SITE FOR RESIDUE RDI A 338 source : AC1 7) chain A residue 162 type sequence N description BINDING SITE FOR RESIDUE RDI A 338 source : AC1 8) chain A residue 163 type sequence L description BINDING SITE FOR RESIDUE RDI A 338 source : AC1 9) chain A residue 199 type sequence F description BINDING SITE FOR RESIDUE RDI A 338 source : AC1 10) chain A residue 245 type sequence T description BINDING SITE FOR RESIDUE RDI A 338 source : AC1 11) chain A residue 247 type sequence I description BINDING SITE FOR RESIDUE RDI A 338 source : AC1 12) chain A residue 107 type BINDING sequence N description BINDING => ECO:0000269|PubMed:15292259, ECO:0000269|PubMed:15951571, ECO:0000269|PubMed:17936703, ECO:0007744|PDB:1TC0, ECO:0007744|PDB:1TC6, ECO:0007744|PDB:1YT0, ECO:0007744|PDB:2O1U, ECO:0007744|PDB:2O1V source Swiss-Prot : SWS_FT_FI1 13) chain A residue 149 type BINDING sequence D description BINDING => ECO:0000269|PubMed:15292259, ECO:0000269|PubMed:15951571, ECO:0000269|PubMed:17936703, ECO:0007744|PDB:1TBW, ECO:0007744|PDB:1TC0, ECO:0007744|PDB:1TC6, ECO:0007744|PDB:1YT0, ECO:0007744|PDB:2O1U, ECO:0007744|PDB:2O1V source Swiss-Prot : SWS_FT_FI2 14) chain A residue 199 type BINDING sequence F description BINDING => ECO:0000269|PubMed:15292259, ECO:0000269|PubMed:15951571, ECO:0000269|PubMed:17936703, ECO:0007744|PDB:1TBW, ECO:0007744|PDB:1TC0, ECO:0007744|PDB:1TC6, ECO:0007744|PDB:1YT0, ECO:0007744|PDB:2O1U, ECO:0007744|PDB:2O1V source Swiss-Prot : SWS_FT_FI2 15) chain A residue 162 type BINDING sequence N description BINDING => ECO:0000269|PubMed:15292259, ECO:0000269|PubMed:15951571, ECO:0000269|PubMed:17936703, ECO:0007744|PDB:1TBW, ECO:0007744|PDB:1TC0, ECO:0007744|PDB:1TC6, ECO:0007744|PDB:2O1U, ECO:0007744|PDB:2O1V source Swiss-Prot : SWS_FT_FI3 16) chain A residue 107 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI8 17) chain A residue 217 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI8 18) chain A residue 94-103 type prosite sequence YKNKEIFLRE description HSP90 Heat shock hsp90 proteins family signature. YkNKEIFLRE source prosite : PS00298 19) chain A residue 168 type MOD_RES sequence K description N6-(2-hydroxyisobutyryl)lysine => ECO:0000250|UniProtKB:P14625 source Swiss-Prot : SWS_FT_FI4 20) chain A residue 172 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:Q66HD0 source Swiss-Prot : SWS_FT_FI5

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