eF-site ID 1qxs-D PDB Code 1qxs Chain D click to enlarge Title CRYSTAL STRUCTURE OF Trypanosoma cruzi GLYCERALDEHYDE-3- PHOSPHATE DEHYDROGENASE COMPLEXED WITH AN ANALOGUE OF 1,3- BisPHOSPHO-D-GLYCERIC ACID Classification OXIDOREDUCTASE Compound Glyceraldehyde 3-phosphate dehydrogenase, glycosomal Source Trypanosoma cruzi (G3PG_TRYCR) Sequence D:  MPIKVGINGFGRIGRMVFQALCEDGLLGTEIDVVAVVDMN TDAEYFAYQMRYDTVHGKFKYEVTTTKSSPSVAKDDTLVV NGHRILCVKAQRNPADLPWGKLGVEYVIESTGLFTAKAAA EGHLRGGARKVVISAPASGGAKTLVMGVNHHEYNPSEHHV VSNASCTTNCLAPIVHVLVKEGFGVQTGLMTTIHSYTATQ KTVDGVSVKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTQ GKLTGMSFRVPTPDVSVVDLTFTAARDTSIQEIDAALKRA SKTYMKGILGYTDEELVSADFINDNRSSIYDSKATLQNNL PKERRFFKIVSWYDNEWGYSHRVVDLVRHMASKDRSARL Description Functional site 1) chain D residue 8 type sequence N description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 2) chain D residue 9 type sequence G description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 3) chain D residue 11 type sequence G description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 4) chain D residue 12 type sequence R description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 5) chain D residue 13 type sequence I description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 6) chain D residue 38 type sequence D description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 7) chain D residue 39 type sequence M description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 8) chain D residue 90 type sequence A description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 9) chain D residue 91 type sequence Q description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 10) chain D residue 110 type sequence S description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 11) chain D residue 111 type sequence T description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 12) chain D residue 112 type sequence G description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 13) chain D residue 113 type sequence L description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 14) chain D residue 134 type sequence S description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 15) chain D residue 135 type sequence A description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 16) chain D residue 166 type sequence C description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 17) chain D residue 198 type sequence A description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 18) chain D residue 335 type sequence N description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 19) chain D residue 339 type sequence Y description BINDING SITE FOR RESIDUE NAD D 861 source : AC2 20) chain D residue 206 type sequence V description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 21) chain D residue 166 type ACT_SITE sequence C description Nucleophile source Swiss-Prot : SWS_FT_FI1 22) chain D residue 335 type BINDING sequence N description BINDING => ECO:0000269|PubMed:12795610, ECO:0000269|PubMed:14622286 source Swiss-Prot : SWS_FT_FI2 23) chain D residue 12 type BINDING sequence R description BINDING => ECO:0000269|PubMed:12795610, ECO:0000269|PubMed:14622286 source Swiss-Prot : SWS_FT_FI2 24) chain D residue 38 type BINDING sequence D description BINDING => ECO:0000269|PubMed:12795610, ECO:0000269|PubMed:14622286 source Swiss-Prot : SWS_FT_FI2 25) chain D residue 91 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:12795610, ECO:0000269|PubMed:14622286 source Swiss-Prot : SWS_FT_FI2 26) chain D residue 134 type BINDING sequence S description BINDING => ECO:0000269|PubMed:12795610, ECO:0000269|PubMed:14622286 source Swiss-Prot : SWS_FT_FI2 27) chain D residue 165 type BINDING sequence S description source Swiss-Prot : SWS_FT_FI3 28) chain D residue 197 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI3 29) chain D residue 226 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI3 30) chain D residue 249 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 31) chain D residue 194 type SITE sequence H description Activates thiol group during catalysis source Swiss-Prot : SWS_FT_FI4

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