eF-site ID 1qxs-A PDB Code 1qxs Chain A click to enlarge Title CRYSTAL STRUCTURE OF Trypanosoma cruzi GLYCERALDEHYDE-3- PHOSPHATE DEHYDROGENASE COMPLEXED WITH AN ANALOGUE OF 1,3- BisPHOSPHO-D-GLYCERIC ACID Classification OXIDOREDUCTASE Compound Glyceraldehyde 3-phosphate dehydrogenase, glycosomal Source null (G3PG_TRYCR) Sequence A:  MPIKVGINGFGRIGRMVFQALCEDGLLGTEIDVVAVVDMN TDAEYFAYQMRYDTVHGKFKYEVTTTKSSPSVAKDDTLVV NGHRILCVKAQRNPADLPWGKLGVEYVIESTGLFTAKAAA EGHLRGGARKVVISAPASGGAKTLVMGVNHHEYNPSEHHV VSNASCTTNCLAPIVHVLVKEGFGVQTGLMTTIHSYTATQ KTVDGVSVKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTQ GKLTGMSFRVPTPDVSVVDLTFTAARDTSIQEIDAALKRA SKTYMKGILGYTDEELVSADFINDNRSSIYDSKATLQNNL PKERRFFKIVSWYDNEWGYSHRVVDLVRHMASKDRSARL Description Functional site 1) chain A residue 9 type sequence G description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 2) chain A residue 11 type sequence G description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 3) chain A residue 12 type sequence R description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 4) chain A residue 13 type sequence I description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 5) chain A residue 37 type sequence V description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 6) chain A residue 38 type sequence D description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 7) chain A residue 39 type sequence M description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 8) chain A residue 90 type sequence A description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 9) chain A residue 91 type sequence Q description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 10) chain A residue 110 type sequence S description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 11) chain A residue 111 type sequence T description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 12) chain A residue 113 type sequence L description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 13) chain A residue 134 type sequence S description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 14) chain A residue 135 type sequence A description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 15) chain A residue 166 type sequence C description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 16) chain A residue 198 type sequence A description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 17) chain A residue 335 type sequence N description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 18) chain A residue 339 type sequence Y description BINDING SITE FOR RESIDUE NAD A 862 source : AC3 19) chain A residue 166 type sequence C description BINDING SITE FOR RESIDUE S70 A 804 source : AC5 20) chain A residue 167 type sequence T description BINDING SITE FOR RESIDUE S70 A 804 source : AC5 21) chain A residue 192 type sequence T description BINDING SITE FOR RESIDUE S70 A 804 source : AC5 22) chain A residue 194 type sequence H description BINDING SITE FOR RESIDUE S70 A 804 source : AC5 23) chain A residue 197 type sequence T description BINDING SITE FOR RESIDUE S70 A 804 source : AC5 24) chain A residue 199 type sequence T description BINDING SITE FOR RESIDUE S70 A 804 source : AC5 25) chain A residue 226 type sequence T description BINDING SITE FOR RESIDUE S70 A 804 source : AC5 26) chain A residue 247 type sequence S description BINDING SITE FOR RESIDUE S70 A 804 source : AC5 27) chain A residue 249 type sequence R description BINDING SITE FOR RESIDUE S70 A 804 source : AC5 28) chain A residue 166 type ACT_SITE sequence C description Nucleophile source Swiss-Prot : SWS_FT_FI1 29) chain A residue 197 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI3 30) chain A residue 226 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI3 31) chain A residue 249 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 32) chain A residue 165 type BINDING sequence S description source Swiss-Prot : SWS_FT_FI3 33) chain A residue 194 type SITE sequence H description Activates thiol group during catalysis source Swiss-Prot : SWS_FT_FI4 34) chain A residue 12 type BINDING sequence R description BINDING => ECO:0000269|PubMed:12795610, ECO:0000269|PubMed:14622286 source Swiss-Prot : SWS_FT_FI2 35) chain A residue 38 type BINDING sequence D description BINDING => ECO:0000269|PubMed:12795610, ECO:0000269|PubMed:14622286 source Swiss-Prot : SWS_FT_FI2 36) chain A residue 91 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:12795610, ECO:0000269|PubMed:14622286 source Swiss-Prot : SWS_FT_FI2 37) chain A residue 134 type BINDING sequence S description BINDING => ECO:0000269|PubMed:12795610, ECO:0000269|PubMed:14622286 source Swiss-Prot : SWS_FT_FI2 38) chain A residue 335 type BINDING sequence N description BINDING => ECO:0000269|PubMed:12795610, ECO:0000269|PubMed:14622286 source Swiss-Prot : SWS_FT_FI2

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