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eF-site ID
|
1q8k_13-A |
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PDB Code
|
1q8k |
|
Model
|
13 |
|
Chain
|
A |
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click to enlarge
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Title
|
Solution structure of alpha subunit of human eIF2 |
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Classification
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TRANSLATION |
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Compound
|
Eukaryotic translation initiation factor 2 subunit 1 |
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Source
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null (IF2A_HUMAN) |
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Sequence
|
A: |
MSCRFYQHKFPEVEDVVMVNVRSIQEMGAYVSLLEYNNIE
GMIHLSELSRRRIRSINKLIRIGRNECVKVIRVDKEKGYI
DLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTK
DEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSIL
DSLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYE
GIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTTLE
RTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDE
TELARQMERLERENAEVDGD
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
279 |
| type |
MOD_RES |
| sequence |
D
|
| description |
Phosphothreonine => ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
2)
|
chain |
A |
| residue |
281 |
| type |
MOD_RES |
| sequence |
D
|
| description |
Phosphothreonine => ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
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3)
|
chain |
A |
| residue |
49 |
| type |
MOD_RES |
| sequence |
E
|
| description |
Phosphoserine; by HRI => ECO:0000250|UniProtKB:P83268
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
52 |
| type |
MOD_RES |
| sequence |
R
|
| description |
Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:24275569
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
A |
| residue |
141 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
6)
|
chain |
A |
| residue |
158 |
| type |
MOD_RES |
| sequence |
D
|
| description |
Phosphoserine => ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|