eF-site ID 1q7b-A PDB Code 1q7b Chain A click to enlarge Title The structure of betaketoacyl-[ACP] reductase from E. coli in complex with NADP+ Classification OXIDOREDUCTASE Compound 3-oxoacyl-[acyl-carrier protein] reductase Source Escherichia coli (strain K12) (FABG_ECOLI) Sequence A:  NFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENG AQAISDYLGANGKGLMLNVTDPASIESVLEKIRAEFGEVD ILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKAV MRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGF SKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGIL AQVPAGRLGGAQEIANAVAFLASDEAAYITGETLHVNGGM YMV Description Functional site 1) chain A residue 233 type sequence E description BINDING SITE FOR RESIDUE CA A 9002 source : AC2 2) chain A residue 234 type sequence T description BINDING SITE FOR RESIDUE CA A 9002 source : AC2 3) chain A residue 145 type sequence N description BINDING SITE FOR RESIDUE CA A 9007 source : AC6 4) chain A residue 12 type sequence G description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 5) chain A residue 14 type sequence S description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 6) chain A residue 15 type sequence R description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 7) chain A residue 17 type sequence I description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 8) chain A residue 37 type sequence T description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 9) chain A residue 58 type sequence L description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 10) chain A residue 59 type sequence N description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 11) chain A residue 60 type sequence V description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 12) chain A residue 86 type sequence N description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 13) chain A residue 87 type sequence A description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 14) chain A residue 88 type sequence G description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 15) chain A residue 89 type sequence I description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 16) chain A residue 136 type sequence I description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 17) chain A residue 137 type sequence G description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 18) chain A residue 138 type sequence S description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 19) chain A residue 151 type sequence Y description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 20) chain A residue 155 type sequence K description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 21) chain A residue 181 type sequence P description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 22) chain A residue 182 type sequence G description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 23) chain A residue 184 type sequence I description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 24) chain A residue 186 type sequence T description BINDING SITE FOR RESIDUE NAP A 1901 source : AC8 25) chain A residue 151 type ACT_SITE sequence Y description Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10001 source Swiss-Prot : SWS_FT_FI1 26) chain A residue 12 type BINDING sequence G description BINDING => ECO:0000269|PubMed:15016358, ECO:0007744|PDB:1Q7B, ECO:0007744|PDB:1Q7C source Swiss-Prot : SWS_FT_FI2 27) chain A residue 37 type BINDING sequence T description BINDING => ECO:0000269|PubMed:15016358, ECO:0007744|PDB:1Q7B, ECO:0007744|PDB:1Q7C source Swiss-Prot : SWS_FT_FI2 28) chain A residue 59 type BINDING sequence N description BINDING => ECO:0000269|PubMed:15016358, ECO:0007744|PDB:1Q7B, ECO:0007744|PDB:1Q7C source Swiss-Prot : SWS_FT_FI2 29) chain A residue 151 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:15016358, ECO:0007744|PDB:1Q7B, ECO:0007744|PDB:1Q7C source Swiss-Prot : SWS_FT_FI2 30) chain A residue 138-166 type prosite sequence SVVGTMGNGGQANYAAAKAGLIGFSKSLA description ADH_SHORT Short-chain dehydrogenases/reductases family signature. SvvgtmgnggQanYAAAKAGLiGFSkSLA source prosite : PS00061 31) chain A residue 50 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI3 32) chain A residue 53 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI3 33) chain A residue 145 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI3 34) chain A residue 233 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI3 35) chain A residue 234 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI3 36) chain A residue 86 type BINDING sequence N description BINDING => ECO:0000269|PubMed:15016358, ECO:0007744|PDB:1Q7B source Swiss-Prot : SWS_FT_FI4 37) chain A residue 138 type BINDING sequence S description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI5 38) chain A residue 184 type BINDING sequence I description BINDING => ECO:0000269|PubMed:15016358 source Swiss-Prot : SWS_FT_FI6

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