|
|
eF-site ID
|
1q6x-B |
|
PDB Code
|
1q6x |
|
Chain
|
B |
|
click to enlarge
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Title
|
Crystal structure of rat choline acetyltransferase |
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Classification
|
TRANSFERASE |
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Compound
|
choline O-acetyltransferase |
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Source
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Rattus norvegicus (Rat) (CLAT_RAT) |
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Sequence
|
B: |
WEELDLPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAI
VKRFGAPGGLGETLQEKLLERQEKTANWVSEYWLNDMYLN
NRLALPVNSSPAVIFARQHFQDTNDQLRFAACLISGVLSY
KTLLDSHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGH
TQDTLVAQKSSIMPEPEHVIVACCNQFFVLDVVINFRRLS
EGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKAR
TVLLKDSTNRDSLDMIERCICLVCLDGPGTGELSDTHRAL
QLLHGGGCSLNGANRWYDKSLQFVVGRDGTCGVVCEHSPF
DGIVLVQCTEHLLKHMMTSNKKLVRADSVSELPAPRRLRW
KCSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIK
KQKYSPDGFIQVALQLAYYRLYQRLVPTYESASIRRFQEG
RVDNIRSATPEALAFVQAMTDHKAAMPASEKLQLLQTAMQ
AQTEYTVMAITGMAIDNHLLALRELARDLCKEPPEMFMDE
TYLMSNRFVLSTSQVPTTMEMFCCYGPVVPNGYGACYNPQ
PEAITFCISSFHSCKETSSVEFAEAVGASLVDMRDLCSSR
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Description
|
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Functional site
|
|
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1)
|
chain |
B |
| residue |
588 |
| type |
|
| sequence |
F
|
| description |
BINDING SITE FOR RESIDUE NA B 1001
|
| source |
: AC1
|
|
|
2)
|
chain |
B |
| residue |
589 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE NA B 1001
|
| source |
: AC1
|
|
|
3)
|
chain |
B |
| residue |
591 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE NA B 1001
|
| source |
: AC1
|
|
|
4)
|
chain |
B |
| residue |
594 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE NA B 1001
|
| source |
: AC1
|
|
|
5)
|
chain |
B |
| residue |
95 |
| type |
catalytic |
| sequence |
Y
|
| description |
605
|
| source |
MCSA : MCSA2
|
|
|
6)
|
chain |
B |
| residue |
108 |
| type |
catalytic |
| sequence |
P
|
| description |
605
|
| source |
MCSA : MCSA2
|
|
|
7)
|
chain |
B |
| residue |
334 |
| type |
catalytic |
| sequence |
H
|
| description |
605
|
| source |
MCSA : MCSA2
|
|
|
8)
|
chain |
B |
| residue |
550 |
| type |
catalytic |
| sequence |
S
|
| description |
605
|
| source |
MCSA : MCSA2
|
|
|
9)
|
chain |
B |
| residue |
334 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Proton acceptor => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
B |
| residue |
412 |
| type |
BINDING |
| sequence |
G
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
11)
|
chain |
B |
| residue |
450 |
| type |
BINDING |
| sequence |
S
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
12)
|
chain |
B |
| residue |
551 |
| type |
BINDING |
| sequence |
Q
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
13)
|
chain |
B |
| residue |
365 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:22673903
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|