eF-site ID 1q5w_2-AB PDB Code 1q5w Model 2 Chain A, B click to enlarge Title Ubiquitin Recognition by Npl4 Zinc-Fingers Classification PROTEIN BINDING Compound homolog of yeast nuclear protein localization 4 Source null (UBIQ_HUMAN) Sequence A:  GSTSAMWACQHCTFMNQPGTGHCEMCSLPRT B:  MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQ QRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG Description Functional site 1) chain A residue 9 type sequence C description BINDING SITE FOR RESIDUE ZN A 32 source : AC1 2) chain A residue 12 type sequence C description BINDING SITE FOR RESIDUE ZN A 32 source : AC1 3) chain A residue 23 type sequence C description BINDING SITE FOR RESIDUE ZN A 32 source : AC1 4) chain A residue 26 type sequence C description BINDING SITE FOR RESIDUE ZN A 32 source : AC1 5) chain B residue 168 type SITE sequence H description Essential for function source Swiss-Prot : SWS_FT_FI2 6) chain B residue 165 type MOD_RES sequence S description Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291 source Swiss-Prot : SWS_FT_FI3 7) chain B residue 163 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106 source Swiss-Prot : SWS_FT_FI12 8) chain B residue 129 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127 source Swiss-Prot : SWS_FT_FI10 9) chain B residue 166 type MOD_RES sequence T description (Microbial infection) ADP-ribosylthreonine => ECO:0000269|PubMed:32330457 source Swiss-Prot : SWS_FT_FI4 10) chain B residue 176 type MOD_RES sequence G description ADP-ribosylglycine => ECO:0000269|PubMed:28525742 source Swiss-Prot : SWS_FT_FI5 11) chain B residue 106 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603 source Swiss-Prot : SWS_FT_FI6 12) chain B residue 176 type CROSSLNK sequence G description Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) source Swiss-Prot : SWS_FT_FI7 13) chain B residue 148 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144 source Swiss-Prot : SWS_FT_FI8 14) chain B residue 111 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144 source Swiss-Prot : SWS_FT_FI8 15) chain B residue 172 type SITE sequence R description Interacts with activating enzyme source Swiss-Prot : SWS_FT_FI1 16) chain B residue 154 type SITE sequence R description Interacts with activating enzyme source Swiss-Prot : SWS_FT_FI1 17) chain B residue 127-152 type prosite sequence KAKIQDKEGIPPDQQRLIFAGKQLED description UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD source prosite : PS00299 18) chain A residue 7-26 type prosite sequence WACQHCTFMNQPGTGHCEMC description ZF_RANBP2_1 Zinc finger RanBP2-type signature. WaCqh..CtfmNqpgtghCemC source prosite : PS01358 19) chain B residue 133 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577 source Swiss-Prot : SWS_FT_FI11 20) chain B residue 127 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860 source Swiss-Prot : SWS_FT_FI9

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