eF-site/Summary 1q1t-C

eF-site ID	1q1t-C
PDB Code	1q1t
Chain	C

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Title	Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex
Classification	PROTEIN TRANSPORT
Compound	Large T antigen
Source	null (TALA_SV40)

Sequence	C:	NQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQ PPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIAS GTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNI AGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNL TWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLA DSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPI VTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKT NIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKA DFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLL SAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGG LDKIEALQRHENESVYKASLNLIEKYF

Description

Functional site


1)	chain	C
	residue	296
	type	BINDING
	sequence	P
	description	BINDING => ECO:0000255\|PROSITE-ProRule:PRU00671
	source	Swiss-Prot : SWS_FT_FI3

2)	chain	C
	residue	307
	type	BINDING
	sequence	L
	description	BINDING => ECO:0000255\|PROSITE-ProRule:PRU00671
	source	Swiss-Prot : SWS_FT_FI3

3)	chain	C
	residue	311
	type	BINDING
	sequence	T
	description	BINDING => ECO:0000255\|PROSITE-ProRule:PRU00671
	source	Swiss-Prot : SWS_FT_FI3

4)	chain	C
	residue	299
	type	BINDING
	sequence	V
	description	BINDING => ECO:0000255\|PROSITE-ProRule:PRU00671
	source	Swiss-Prot : SWS_FT_FI3

5)	chain	C
	residue	420
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000255\|PROSITE-ProRule:PRU00551
	source	Swiss-Prot : SWS_FT_FI4

6)	chain	C
	residue	100
	type	MOD_RES
	sequence	A
	description	Phosphoserine; by host => ECO:0000269\|PubMed:2160857, ECO:0000269\|PubMed:2838952
	source	Swiss-Prot : SWS_FT_FI5

7)	chain	C
	residue	106
	type	MOD_RES
	sequence	R
	description	Phosphoserine; by host => ECO:0000269\|PubMed:2160857, ECO:0000269\|PubMed:2838952
	source	Swiss-Prot : SWS_FT_FI5

8)	chain	C
	residue	117
	type	MOD_RES
	sequence	R
	description	Phosphoserine; by host => ECO:0000269\|PubMed:2160857, ECO:0000269\|PubMed:2838952
	source	Swiss-Prot : SWS_FT_FI5

9)	chain	C
	residue	114
	type	MOD_RES
	sequence	N
	description	Phosphoserine; by host => ECO:0000269\|PubMed:2160857
	source	Swiss-Prot : SWS_FT_FI6

10)	chain	C
	residue	118
	type	MOD_RES
	sequence	A
	description	Phosphothreonine; by host => ECO:0000269\|PubMed:2160857, ECO:0000269\|PubMed:2552322, ECO:0000269\|PubMed:2838952, ECO:0000269\|PubMed:8648725
	source	Swiss-Prot : SWS_FT_FI7

11)	chain	C
	residue	133-248
	type	DNA_BIND
	sequence	CSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLA SPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLAL LAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDA
	description	T-ag OBD => ECO:0000255\|PROSITE-ProRule:PRU00620
	source	Swiss-Prot : SWS_FT_FI1

12)	chain	C
	residue	259-351
	type	ZN_FING
	sequence	LLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQL VKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALA VFPSLLTNPKTNI
	description	T-ag D1-type => ECO:0000255\|PROSITE-ProRule:PRU00671
	source	Swiss-Prot : SWS_FT_FI2