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eF-site ID
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1pzu-BDHILMTVWXYZ |
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PDB Code
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1pzu |
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Chain
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B, D, H, I, L, M, T, V, W, X, Y, Z |
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click to enlarge
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Title
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An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site |
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Classification
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TRANSCRIPTION/DNA |
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Compound
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5'-D(*TP*TP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*A)-3' |
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Source
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Homo sapiens (Human) (1PZU) |
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Sequence
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B: |
WPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG
GHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHR
ITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGI
LKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIV
SLQTASNPIECSQELPMVERQDTDSCLVYGGQQMILTGQN
FTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEI
PEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPV
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| D: |
WPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG
GHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHR
ITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGI
LKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIV
SLQTASNPIECSQELPMVERQDTDSCLVYGGQQMILTGQN
FTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEI
PEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPV
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| H: |
WPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG
GHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHR
ITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGI
LKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIV
SLQTASNPIECSQELPMVERQDTDSCLVYGGQQMILTGQN
FTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEI
PEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPV
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| I: |
WPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG
GHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHR
ITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGI
LKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIV
SLQTASNPIECSQELPMVERQDTDSCLVYGGQQMILTGQN
FTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEI
PEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPV
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| L: |
WPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG
GHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHR
ITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGI
LKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIV
SLQTASNPIECSQELPMVERQDTDSCLVYGGQQMILTGQN
FTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEI
PEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPV
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| M: |
WPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG
GHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHR
ITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGI
LKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIV
SLQTASNPIECSQELPMVERQDTDSCLVYGGQQMILTGQN
FTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEI
PEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPV
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| T: |
TTGAGGAATTTCCA
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| V: |
TTGAGGAATTTCCA
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| W: |
AATGGAAATTCCTC
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| X: |
TTGAGGAATTTCCA
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| Y: |
AATGGAAATTCCTC
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| Z: |
AATGGAAATTCCTC
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Description
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Functional site
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1)
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chain |
B |
| residue |
421-428 |
| type |
DNA_BIND |
| sequence |
RAHYETEG
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| description |
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
D |
| residue |
421-428 |
| type |
DNA_BIND |
| sequence |
RAHYETEG
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| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
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3)
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chain |
H |
| residue |
421-428 |
| type |
DNA_BIND |
| sequence |
RAHYETEG
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| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
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4)
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chain |
I |
| residue |
421-428 |
| type |
DNA_BIND |
| sequence |
RAHYETEG
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| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
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5)
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chain |
L |
| residue |
421-428 |
| type |
DNA_BIND |
| sequence |
RAHYETEG
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| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
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6)
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chain |
M |
| residue |
421-428 |
| type |
DNA_BIND |
| sequence |
RAHYETEG
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| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
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