|
|
eF-site ID
|
1pvq-B |
|
PDB Code
|
1pvq |
|
Chain
|
B |
|
click to enlarge
|
|
|
Title
|
BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7 |
|
Classification
|
RECOMBINATION/DNA |
|
Compound
|
DNA 34-MER |
|
Source
|
null (RECR_BPP1) |
|
|
Sequence
|
B: |
TSDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKL
NNRKWFPAEPEDVRDYLLYLQARGLAVKTIQQHLGQLNML
HRRSGLPRPSDSNAVSLVMRRIRKENVDAGERAKQALAFE
RTDFDQVRSLMENSDRCQDIRNLAFLGIAYNTLLRLAEIA
RIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVT
KLVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSN
SALGGIFGATHRLIYGAKDDSGQRYLAWSGHSARVGAARD
MARAGVSIPEIMQAGGWTNVNIVMNYIRNTGAMVRLLED
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
173 |
| type |
ACT_SITE |
| sequence |
R
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01246
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
289 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01246
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
292 |
| type |
ACT_SITE |
| sequence |
R
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01246
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
B |
| residue |
315 |
| type |
ACT_SITE |
| sequence |
W
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01246
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
B |
| residue |
324 |
| type |
ACT_SITE |
| sequence |
Y
|
| description |
O-(3'-phospho-DNA)-tyrosine intermediate => ECO:0000255|PROSITE-ProRule:PRU01246
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|