eF-site ID 1pre-AB PDB Code 1pre Chain A, B click to enlarge Title PROAEROLYSIN Classification TOXIN (HEMOLYTIC POLYPEPTIDE) Compound PROAEROLYSIN Source Aeromonas hydrophila (AERA_AERHY) Sequence A:  EPVYPDQLRLFSLGQGVCGDKYRPVNREEAQSVKSNIVGM MGQWQISGLANGWVIMGPGYNGEIKPGTASNTWCYPTNPV TGEIPTLSALDIPDGDEVDVQWRLVHDSANFIKPTSYLAH YLGYAWVGGNHSQYVGEDMDVTRDGDGWVIRGNNDGGCDG YRCGDKTAIKVSNFAYNLDPDSFKHGDVTQSDRQLVKTVV GWAVNDPQSGYDVTLRYDTATNWSKTNTYGLSEKVTTKNK FKWPLVGETELSIEIAANQSWASQNGGSTTTSLSQSVRPT VPARSKIPVKIELYKADISYPYEFKADVSYDLTLSGFLRW GGNAWYTHPDNRPNWNHTFVIGPYKDKASSIRYQWDKRYI PGEVKWWDWNWTIQQNGLSTMQNNLARVLRPVRAGITGDF SAESQFAGNIEIGAPVPLGLRLEIPLDAQELSGLGFNNVS LSVTPAANQ B:  EPVYPDQLRLFSLGQGVCGDKYRPVNREEAQSVKSNIVGM MGQWQISGLANGWVIMGPGYNGEIKPGTASNTWCYPTNPV TGEIPTLSALDIPDGDEVDVQWRLVHDSANFIKPTSYLAH YLGYAWVGGNHSQYVGEDMDVTRDGDGWVIRGNNDGGCDG YRCGDKTAIKVSNFAYNLDPDSFKHGDVTQSDRQLVKTVV GWAVNDSDTPQSGYDVTLRYDTATNWSKTNTYGLSEKVTT KNKFKWPLVGETELSIEIAANQSWASQNGGSTTTSLSQSV RPTVPARSKIPVKIELYKADISYPYEFKADVSYDLTLSGF LRWGGNAWYTHPDNRPNWNHTFVIGPYKDKASSIRYQWDK RYIPGEVKWWDWNWTIQQNGLSTMQNNLARVLRPVRAGIT GDFSAESQFAGNIEIGAPVPLAALRLEIPLDAQELSGLGF NNVSLSVTPAA Description (1)  PROAEROLYSIN Functional site 1) chain A residue 132 type SITE sequence H description Important for oligomerization source Swiss-Prot : SWS_FT_FI1 2) chain B residue 132 type SITE sequence H description Important for oligomerization source Swiss-Prot : SWS_FT_FI1 3) chain A residue 351 type SITE sequence K description Important for heptamerization source Swiss-Prot : SWS_FT_FI2 4) chain A residue 367 type SITE sequence E description Important for heptamerization source Swiss-Prot : SWS_FT_FI2 5) chain B residue 351 type SITE sequence K description Important for heptamerization source Swiss-Prot : SWS_FT_FI2 6) chain B residue 367 type SITE sequence E description Important for heptamerization source Swiss-Prot : SWS_FT_FI2 7) chain A residue 223-232 type prosite sequence TATNWSKTNT description AEROLYSIN Aerolysin type toxins signature. TatNWskTNT source prosite : PS00274 8) chain A residue 95-101 type prosite sequence DGDEVDV description PPASE Inorganic pyrophosphatase signature. DGDEVDV source prosite : PS00387

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