|
|
eF-site ID
|
1pre-A |
|
PDB Code
|
1pre |
|
Chain
|
A |
|
click to enlarge
|
|
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Title
|
PROAEROLYSIN |
|
Classification
|
TOXIN (HEMOLYTIC POLYPEPTIDE) |
|
Compound
|
PROAEROLYSIN |
|
Source
|
null (AERA_AERHY) |
|
|
Sequence
|
A: |
EPVYPDQLRLFSLGQGVCGDKYRPVNREEAQSVKSNIVGM
MGQWQISGLANGWVIMGPGYNGEIKPGTASNTWCYPTNPV
TGEIPTLSALDIPDGDEVDVQWRLVHDSANFIKPTSYLAH
YLGYAWVGGNHSQYVGEDMDVTRDGDGWVIRGNNDGGCDG
YRCGDKTAIKVSNFAYNLDPDSFKHGDVTQSDRQLVKTVV
GWAVNDPQSGYDVTLRYDTATNWSKTNTYGLSEKVTTKNK
FKWPLVGETELSIEIAANQSWASQNGGSTTTSLSQSVRPT
VPARSKIPVKIELYKADISYPYEFKADVSYDLTLSGFLRW
GGNAWYTHPDNRPNWNHTFVIGPYKDKASSIRYQWDKRYI
PGEVKWWDWNWTIQQNGLSTMQNNLARVLRPVRAGITGDF
SAESQFAGNIEIGAPVPLGLRLEIPLDAQELSGLGFNNVS
LSVTPAANQ
|
|
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Description
|
(1) |
PROAEROLYSIN
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
223-232 |
| type |
prosite |
| sequence |
TATNWSKTNT
|
| description |
AEROLYSIN Aerolysin type toxins signature. TatNWskTNT
|
| source |
prosite : PS00274
|
|
|
2)
|
chain |
A |
| residue |
95-101 |
| type |
prosite |
| sequence |
DGDEVDV
|
| description |
PPASE Inorganic pyrophosphatase signature. DGDEVDV
|
| source |
prosite : PS00387
|
|
|
3)
|
chain |
A |
| residue |
132 |
| type |
SITE |
| sequence |
H
|
| description |
Important for oligomerization
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
367 |
| type |
SITE |
| sequence |
E
|
| description |
Important for heptamerization
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
A |
| residue |
351 |
| type |
SITE |
| sequence |
K
|
| description |
Important for heptamerization
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|