eF-site ID 1pke-B PDB Code 1pke Chain B click to enlarge Title Crystal Structure of E. coli purine nucleoside phosphorylase complexed with 2-fluoro-2'-deoxyadenosine and sulfate/phosphate Classification TRANSFERASE Compound Purine nucleoside phosphorylase DeoD-type Source ORGANISM_SCIENTIFIC: Escherichia coli O157:H7; Sequence B:  ATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVN NVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDF GVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRF KDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFY SPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTIC TVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDK Description Functional site 1) chain B residue 20 type sequence G description BINDING SITE FOR RESIDUE PO4 B 450 source : AC3 2) chain B residue 87 type sequence R description BINDING SITE FOR RESIDUE PO4 B 450 source : AC3 3) chain B residue 89 type sequence G description BINDING SITE FOR RESIDUE PO4 B 450 source : AC3 4) chain B residue 90 type sequence S description BINDING SITE FOR RESIDUE PO4 B 450 source : AC3 5) chain B residue 64 type sequence M description BINDING SITE FOR RESIDUE 2FD B 447 source : AC4 6) chain B residue 90 type sequence S description BINDING SITE FOR RESIDUE 2FD B 447 source : AC4 7) chain B residue 91 type sequence C description BINDING SITE FOR RESIDUE 2FD B 447 source : AC4 8) chain B residue 92 type sequence G description BINDING SITE FOR RESIDUE 2FD B 447 source : AC4 9) chain B residue 159 type sequence F description BINDING SITE FOR RESIDUE 2FD B 447 source : AC4 10) chain B residue 178 type sequence V description BINDING SITE FOR RESIDUE 2FD B 447 source : AC4 11) chain B residue 180 type sequence M description BINDING SITE FOR RESIDUE 2FD B 447 source : AC4 12) chain B residue 181 type sequence E description BINDING SITE FOR RESIDUE 2FD B 447 source : AC4 13) chain B residue 204 type sequence D description BINDING SITE FOR RESIDUE 2FD B 447 source : AC4 14) chain B residue 43 type sequence R description BINDING SITE FOR RESIDUE PO4 C 451 source : AC5 15) chain B residue 4 type sequence H description BINDING SITE FOR RESIDUE 2FD C 448 source : AC6 16) chain B residue 43 type sequence R description BINDING SITE FOR RESIDUE 2FD C 448 source : AC6 17) chain B residue 204 type ACT_SITE sequence D description Proton donor => ECO:0000255|HAMAP-Rule:MF_01627 source Swiss-Prot : SWS_FT_FI1 18) chain B residue 4 type BINDING sequence H description BINDING => ECO:0000269|PubMed:12937174 source Swiss-Prot : SWS_FT_FI2 19) chain B residue 43 type BINDING sequence R description BINDING => ECO:0000269|PubMed:12937174 source Swiss-Prot : SWS_FT_FI2 20) chain B residue 203 type BINDING sequence S description in other chain => ECO:0000269|PubMed:12937174 source Swiss-Prot : SWS_FT_FI3 21) chain B residue 20 type BINDING sequence G description in other chain => ECO:0000269|PubMed:12937174 source Swiss-Prot : SWS_FT_FI3 22) chain B residue 24 type BINDING sequence R description in other chain => ECO:0000269|PubMed:12937174 source Swiss-Prot : SWS_FT_FI3 23) chain B residue 87 type BINDING sequence R description in other chain => ECO:0000269|PubMed:12937174 source Swiss-Prot : SWS_FT_FI3 24) chain B residue 179 type BINDING sequence E description in other chain => ECO:0000269|PubMed:12937174 source Swiss-Prot : SWS_FT_FI3 25) chain B residue 217 type SITE sequence R description Important for catalytic activity => ECO:0000255|HAMAP-Rule:MF_01627 source Swiss-Prot : SWS_FT_FI4 26) chain B residue 26 type MOD_RES sequence K description N6-acetyllysine => ECO:0000255|HAMAP-Rule:MF_01627 source Swiss-Prot : SWS_FT_FI5

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