eF-site ID 1pgj-A PDB Code 1pgj Chain A click to enlarge Title X-RAY STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE FROM THE PROTOZOAN PARASITE T. BRUCEI Classification OXIDOREDUCTASE Compound 6-PHOSPHOGLUCONATE DEHYDROGENASE Source Trypanosoma brucei brucei (6PGD_TRYBB) Sequence A:  SMDVGVVGLGVMGANLALNIAEKGFKVAVFNRTYSKSEEF MKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAGA ATDSTIEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAA GLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEA AAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIWG EVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAA ARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAP SLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNKS PSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLN LPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQ TEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMFT PTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ Description Functional site 1) chain A residue 193 type sequence Y description BINDING SITE FOR RESIDUE SO4 A 505 source : AC1 2) chain A residue 261 type sequence S description BINDING SITE FOR RESIDUE SO4 A 505 source : AC1 3) chain A residue 262 type sequence K description BINDING SITE FOR RESIDUE SO4 A 505 source : AC1 4) chain A residue 289 type sequence R description BINDING SITE FOR RESIDUE SO4 A 505 source : AC1 5) chain A residue 104 type sequence N description BINDING SITE FOR RESIDUE SO4 A 507 source : AC2 6) chain A residue 185 type sequence K description BINDING SITE FOR RESIDUE SO4 A 507 source : AC2 7) chain A residue 189 type sequence N description BINDING SITE FOR RESIDUE SO4 A 507 source : AC2 8) chain A residue 453 type sequence R description BINDING SITE FOR RESIDUE SO4 B 505 source : AC3 9) chain A residue 459 type sequence H description BINDING SITE FOR RESIDUE SO4 B 505 source : AC3 10) chain A residue 185 type ACT_SITE sequence K description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 11) chain A residue 192 type ACT_SITE sequence E description Proton donor => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 12) chain A residue 8 type BINDING sequence G description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 13) chain A residue 31 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 14) chain A residue 76 type BINDING sequence V description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 15) chain A residue 453 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 16) chain A residue 459 type BINDING sequence H description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 17) chain A residue 104 type BINDING sequence N description in other chain => ECO:0000250 source Swiss-Prot : SWS_FT_FI4 18) chain A residue 130 type BINDING sequence S description in other chain => ECO:0000250 source Swiss-Prot : SWS_FT_FI4 19) chain A residue 188 type BINDING sequence H description in other chain => ECO:0000250 source Swiss-Prot : SWS_FT_FI4 20) chain A residue 193 type BINDING sequence Y description in other chain => ECO:0000250 source Swiss-Prot : SWS_FT_FI4 21) chain A residue 262 type BINDING sequence K description in other chain => ECO:0000250 source Swiss-Prot : SWS_FT_FI4 22) chain A residue 289 type BINDING sequence R description in other chain => ECO:0000250 source Swiss-Prot : SWS_FT_FI4 23) chain A residue 255-267 type prosite sequence VMDRIGSKGTGLW description 6PGD 6-phosphogluconate dehydrogenase signature. VmDriGSKGTGlW source prosite : PS00461

Display surface Download Links