eF-site ID 1pdw-H
PDB Code 1pdw
Chain H

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Title Crystal structure of human DJ-1, P 1 21 1 space group
Classification PROTEIN BINDING
Compound DJ-1
Source Homo sapiens (Human) (PARK7_HUMAN)
Sequence H:  ASKRALVILAKGAEEXETVIPVDVXRRAGIKVTVAGLAGK
DPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQN
LSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGS
KVTTHPLAKDKXXNGGHYTYSENRVEKDGLILTSRGPGTS
FEFALAIVEALNGKEVAAQVKAPLVLK
Description (1)  DJ-1


Functional site

1) chain H
residue 3267
type MOD_RES
sequence Y
description Phosphotyrosine => ECO:0007744|PubMed:15592455
source Swiss-Prot : SWS_FT_FI5

2) chain H
residue 3306
type MOD_RES
sequence C
description Cysteine sulfinic acid (-SO2H); alternate => ECO:0000269|PubMed:12939276
source Swiss-Prot : SWS_FT_FI6

3) chain H
residue 3348
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000250|UniProtKB:Q99LX0
source Swiss-Prot : SWS_FT_FI7

4) chain H
residue 3306
type ACT_SITE
sequence C
description Nucleophile => ECO:0000305|PubMed:20304780, ECO:0000305|PubMed:25416785
source Swiss-Prot : SWS_FT_FI1

5) chain H
residue 3326
type ACT_SITE
sequence H
description ACT_SITE => ECO:0000305|PubMed:20304780
source Swiss-Prot : SWS_FT_FI2

6) chain H
residue 3349
type SITE
sequence D
description Cleavage; by CASP6 => ECO:0000250|UniProtKB:Q99LX0
source Swiss-Prot : SWS_FT_FI3

7) chain H
residue 3202
type MOD_RES
sequence A
description N-acetylalanine => ECO:0007744|PubMed:25944712
source Swiss-Prot : SWS_FT_FI4

8) chain H
residue 3330
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:15976810
source Swiss-Prot : SWS_FT_FI11

9) chain H
residue 3382
type MOD_RES
sequence K
description N6-succinyllysine => ECO:0000250|UniProtKB:Q99LX0
source Swiss-Prot : SWS_FT_FI8

10) chain H
residue 3246
type LIPID
sequence C
description S-palmitoyl cysteine => ECO:0000269|PubMed:23847046
source Swiss-Prot : SWS_FT_FI9

11) chain H
residue 3253
type LIPID
sequence C
description S-palmitoyl cysteine => ECO:0000269|PubMed:23847046
source Swiss-Prot : SWS_FT_FI9

12) chain H
residue 3306
type LIPID
sequence C
description S-palmitoyl cysteine; alternate => ECO:0000269|PubMed:23847046
source Swiss-Prot : SWS_FT_FI10


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