eF-site ID 1p6n-B PDB Code 1p6n Chain B click to enlarge Title Bovine endothelial NOS heme domain with L-N(omega)-nitroarginine-(4R)-amino-L-proline amide bound Classification OXIDOREDUCTASE Compound Nitric-oxide synthase, endothelial Source null (NOS3_BOVIN) Sequence B:  KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLP RPPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAE VASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVF DARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAP GRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQ HGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLE HPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGW YMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKD KAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQK ARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQ PDPW Description Functional site 1) chain B residue 83 type sequence Y description BINDING SITE FOR RESIDUE CAC B 852 source : AC3 2) chain B residue 324 type sequence W description BINDING SITE FOR RESIDUE CAC B 852 source : AC3 3) chain B residue 384 type sequence C description BINDING SITE FOR RESIDUE CAC B 852 source : AC3 4) chain B residue 358 type sequence W description BINDING SITE FOR RESIDUE ACT B 861 source : AC4 5) chain B residue 428 type sequence S description BINDING SITE FOR RESIDUE ACT B 861 source : AC4 6) chain B residue 96 type sequence C description BINDING SITE FOR RESIDUE ZN B 900 source : AC5 7) chain B residue 101 type sequence C description BINDING SITE FOR RESIDUE ZN B 900 source : AC5 8) chain B residue 462 type sequence F description BINDING SITE FOR RESIDUE H4B A 760 source : AC7 9) chain B residue 463 type sequence H description BINDING SITE FOR RESIDUE H4B A 760 source : AC7 10) chain B residue 464 type sequence Q description BINDING SITE FOR RESIDUE H4B A 760 source : AC7 11) chain B residue 465 type sequence E description BINDING SITE FOR RESIDUE H4B A 760 source : AC7 12) chain B residue 180 type sequence W description BINDING SITE FOR RESIDUE HEM B 500 source : AC9 13) chain B residue 185 type sequence R description BINDING SITE FOR RESIDUE HEM B 500 source : AC9 14) chain B residue 186 type sequence C description BINDING SITE FOR RESIDUE HEM B 500 source : AC9 15) chain B residue 228 type sequence S description BINDING SITE FOR RESIDUE HEM B 500 source : AC9 16) chain B residue 355 type sequence F description BINDING SITE FOR RESIDUE HEM B 500 source : AC9 17) chain B residue 356 type sequence S description BINDING SITE FOR RESIDUE HEM B 500 source : AC9 18) chain B residue 358 type sequence W description BINDING SITE FOR RESIDUE HEM B 500 source : AC9 19) chain B residue 363 type sequence E description BINDING SITE FOR RESIDUE HEM B 500 source : AC9 20) chain B residue 449 type sequence W description BINDING SITE FOR RESIDUE HEM B 500 source : AC9 21) chain B residue 477 type sequence Y description BINDING SITE FOR RESIDUE HEM B 500 source : AC9 22) chain B residue 104 type sequence S description BINDING SITE FOR RESIDUE H4B B 761 source : BC1 23) chain B residue 367 type sequence R description BINDING SITE FOR RESIDUE H4B B 761 source : BC1 24) chain B residue 448 type sequence A description BINDING SITE FOR RESIDUE H4B B 761 source : BC1 25) chain B residue 449 type sequence W description BINDING SITE FOR RESIDUE H4B B 761 source : BC1 26) chain B residue 249 type sequence Q description BINDING SITE FOR RESIDUE DP9 B 800 source : BC2 27) chain B residue 336 type sequence P description BINDING SITE FOR RESIDUE DP9 B 800 source : BC2 28) chain B residue 355 type sequence F description BINDING SITE FOR RESIDUE DP9 B 800 source : BC2 29) chain B residue 356 type sequence S description BINDING SITE FOR RESIDUE DP9 B 800 source : BC2 30) chain B residue 357 type sequence G description BINDING SITE FOR RESIDUE DP9 B 800 source : BC2 31) chain B residue 358 type sequence W description BINDING SITE FOR RESIDUE DP9 B 800 source : BC2 32) chain B residue 363 type sequence E description BINDING SITE FOR RESIDUE DP9 B 800 source : BC2 33) chain B residue 477 type sequence Y description BINDING SITE FOR RESIDUE DP9 B 800 source : BC2 34) chain B residue 76 type sequence W description BINDING SITE FOR RESIDUE GOL B 880 source : BC3 35) chain B residue 367 type sequence R description BINDING SITE FOR RESIDUE GOL B 882 source : BC4 36) chain B residue 373 type sequence H description BINDING SITE FOR RESIDUE GOL B 882 source : BC4 37) chain B residue 187 type BINDING sequence V description axial binding residue => ECO:0000250|UniProtKB:P29474 source Swiss-Prot : SWS_FT_FI3 38) chain B residue 97 type BINDING sequence T description BINDING => ECO:0000250|UniProtKB:P35228 source Swiss-Prot : SWS_FT_FI1 39) chain B residue 102 type BINDING sequence L description BINDING => ECO:0000250|UniProtKB:P35228 source Swiss-Prot : SWS_FT_FI1 40) chain B residue 105 type BINDING sequence L description BINDING => ECO:0000250|UniProtKB:P29474 source Swiss-Prot : SWS_FT_FI2 41) chain B residue 250 type BINDING sequence L description BINDING => ECO:0000250|UniProtKB:P29474 source Swiss-Prot : SWS_FT_FI2 42) chain B residue 359 type BINDING sequence Y description BINDING => ECO:0000250|UniProtKB:P29474 source Swiss-Prot : SWS_FT_FI2 43) chain B residue 360 type BINDING sequence M description BINDING => ECO:0000250|UniProtKB:P29474 source Swiss-Prot : SWS_FT_FI2 44) chain B residue 364 type BINDING sequence I description BINDING => ECO:0000250|UniProtKB:P29474 source Swiss-Prot : SWS_FT_FI2 45) chain B residue 369 type BINDING sequence L description BINDING => ECO:0000250|UniProtKB:P29474 source Swiss-Prot : SWS_FT_FI2 46) chain B residue 449 type BINDING sequence W description BINDING => ECO:0000250|UniProtKB:P29474 source Swiss-Prot : SWS_FT_FI2 47) chain B residue 450 type BINDING sequence I description BINDING => ECO:0000250|UniProtKB:P29474 source Swiss-Prot : SWS_FT_FI2 48) chain B residue 463 type BINDING sequence H description BINDING => ECO:0000250|UniProtKB:P29474 source Swiss-Prot : SWS_FT_FI2 49) chain B residue 478 type BINDING sequence Q description BINDING => ECO:0000250|UniProtKB:P29474 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links