eF-site ID 1p2p-A PDB Code 1p2p Chain A click to enlarge Title STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2 AT 2.6 ANGSTROMS RESOLUTION AND COMPARISON WITH BOVINE PHOSPHOLIPASE A2 Classification CARBOXYLIC ESTER HYDROLASE Compound PHOSPHOLIPASE A2 Source Sus scrofa (Pig) (PA21B_PIG) Sequence A:  ALWQFRSMIKCAIPGSHPLMDFNNYGCYCGLGGSGTPVDE LDRCCETHDNCYRDAKNLDSCKFLVDNPYTESYSYSCSNT EITCNSKNNACEAFICNCDRNAAICFSKAPYNKEHKNLDT KKYC Description (1)  PHOSPHOLIPASE A2 (E.C.3.1.1.4) (PHOSPHATIDE ACYL-HYDROLASE) Functional site 1) chain A residue 28 type sequence Y description BINDING SITE FOR RESIDUE CA A 125 source : AC1 2) chain A residue 30 type sequence G description BINDING SITE FOR RESIDUE CA A 125 source : AC1 3) chain A residue 32 type sequence G description BINDING SITE FOR RESIDUE CA A 125 source : AC1 4) chain A residue 49 type sequence D description BINDING SITE FOR RESIDUE CA A 125 source : AC1 5) chain A residue 72 type sequence S description BINDING SITE FOR RESIDUE CA A 126 source : AC2 6) chain A residue 72 type sequence S description BINDING SITE FOR RESIDUE CA A 126 source : AC2 7) chain A residue 92 type sequence E description BINDING SITE FOR RESIDUE CA A 126 source : AC2 8) chain A residue 92 type sequence E description BINDING SITE FOR RESIDUE CA A 126 source : AC2 9) chain A residue 28 type catalytic sequence Y description 83 source MCSA : MCSA1 10) chain A residue 30 type catalytic sequence G description 83 source MCSA : MCSA1 11) chain A residue 32 type catalytic sequence G description 83 source MCSA : MCSA1 12) chain A residue 48 type catalytic sequence H description 83 source MCSA : MCSA1 13) chain A residue 49 type catalytic sequence D description 83 source MCSA : MCSA1 14) chain A residue 52 type catalytic sequence Y description 83 source MCSA : MCSA1 15) chain A residue 73 type catalytic sequence Y description 83 source MCSA : MCSA1 16) chain A residue 99 type catalytic sequence D description 83 source MCSA : MCSA1 17) chain A residue 44-51 type prosite sequence CCETHDNC description PA2_HIS Phospholipase A2 histidine active site. CCEtHDnC source prosite : PS00118 18) chain A residue 95-105 type prosite sequence ICNCDRNAAIC description PA2_ASP Phospholipase A2 aspartic acid active site. ICNCDRNAaIC source prosite : PS00119 19) chain A residue 48 type ACT_SITE sequence H description ACT_SITE => ECO:0000269|PubMed:6876174 source Swiss-Prot : SWS_FT_FI1 20) chain A residue 99 type ACT_SITE sequence D description ACT_SITE => ECO:0000269|PubMed:6876174 source Swiss-Prot : SWS_FT_FI1 21) chain A residue 28 type BINDING sequence Y description BINDING => ECO:0000250|UniProtKB:P00593 source Swiss-Prot : SWS_FT_FI2 22) chain A residue 30 type BINDING sequence G description BINDING => ECO:0000250|UniProtKB:P00593 source Swiss-Prot : SWS_FT_FI2 23) chain A residue 32 type BINDING sequence G description BINDING => ECO:0000250|UniProtKB:P00593 source Swiss-Prot : SWS_FT_FI2 24) chain A residue 49 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:P00593 source Swiss-Prot : SWS_FT_FI2 25) chain A residue 56 type LIPID sequence K description N6-palmitoyl lysine => ECO:0000269|PubMed:2498336 source Swiss-Prot : SWS_FT_FI3

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