eF-site ID 1oqn-ABCD PDB Code 1oqn Chain A, B, C, D click to enlarge Title Crystal structure of the phosphotyrosine binding domain (PTB) of mouse Disabled 1 (Dab1) Classification SIGNALING PROTEIN Compound Disabled homolog 1 Source Mus musculus (Mouse) (A4_RAT) Sequence A:  RSEATLIKRFKGEGVRYKAKLIGIDEVSAARGDKLCQDSM MKLKGVVAGARSKGEHKQKIFLTISFGGIKIFDEKTGALQ HHHAVHEISYIAKDITDHRAFGYVCGKEGNHRFVAIKTAQ AAEPVILDLRDLFQLIYELKQREELEKKAQ B:  DRSEATLIKRFKGEGVRYKAKLIGIDEVSAARGDKLCQDS MMKLKGVVAGARSKGEHKQKIFLTISFGGIKIFDEKTGAL QHHHAVHEISYIAKDITDHRAFGYVCGKEGNHRFVAIKTA QAAEPVILDLRDLFQLIYELKQREELEKKAQ C:  NGYENPTYK D:  NGYENPTYK Description Functional site 1) chain A residue 1045 type sequence K description BINDING SITE FOR RESIDUE I3P A 1601 source : AC1 2) chain A residue 1076 type sequence R description BINDING SITE FOR RESIDUE I3P A 1601 source : AC1 3) chain A residue 1081 type sequence H description BINDING SITE FOR RESIDUE I3P A 1601 source : AC1 4) chain A residue 1082 type sequence K description BINDING SITE FOR RESIDUE I3P A 1601 source : AC1 5) chain A residue 1124 type sequence R description BINDING SITE FOR RESIDUE I3P A 1601 source : AC1 6) chain A residue 1142 type sequence K description BINDING SITE FOR RESIDUE I3P A 1601 source : AC1 7) chain B residue 1059 type sequence K description BINDING SITE FOR RESIDUE I3P A 1601 source : AC1 8) chain A residue 1059 type sequence K description BINDING SITE FOR RESIDUE I3P B 1602 source : AC2 9) chain A residue 1173 type sequence K description BINDING SITE FOR RESIDUE I3P B 1602 source : AC2 10) chain B residue 1045 type sequence K description BINDING SITE FOR RESIDUE I3P B 1602 source : AC2 11) chain B residue 1076 type sequence R description BINDING SITE FOR RESIDUE I3P B 1602 source : AC2 12) chain B residue 1081 type sequence H description BINDING SITE FOR RESIDUE I3P B 1602 source : AC2 13) chain B residue 1082 type sequence K description BINDING SITE FOR RESIDUE I3P B 1602 source : AC2 14) chain B residue 1124 type sequence R description BINDING SITE FOR RESIDUE I3P B 1602 source : AC2 15) chain C residue 1502-1509 type prosite sequence GYENPTYK description APP_INTRA Amyloid precursor protein (APP) intracellular domain signature. GYENPTYK source prosite : PS00320 16) chain C residue 1503 type MOD_RES sequence Y description Phosphotyrosine; by ABL1 => ECO:0000250|UniProtKB:P12023 source Swiss-Prot : SWS_FT_FI1 17) chain D residue 1503 type MOD_RES sequence Y description Phosphotyrosine; by ABL1 => ECO:0000250|UniProtKB:P12023 source Swiss-Prot : SWS_FT_FI1 18) chain C residue 1509 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:22847417 source Swiss-Prot : SWS_FT_FI2 19) chain D residue 1509 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:22847417 source Swiss-Prot : SWS_FT_FI2

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