eF-site ID 1oo6-B PDB Code 1oo6 Chain B click to enlarge Title Nitroreductase from e-coli in complex with the dinitrobenzamide prodrug SN23862 Classification OXIDOREDUCTASE Compound Oxygen-insensitive NAD(P)H nitroreductase Source null (NFNB_ECOLI) Sequence B:  MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSS TNSQPWHFIVASTEEGKARVAKSAAGNYVFNERKMLDASH VVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKG RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLD AVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFN ATLPKSRLPQNITLTEV Description Functional site 1) chain B residue 38 type sequence P description BINDING SITE FOR RESIDUE FMN A 218 source : AC1 2) chain B residue 39 type sequence S description BINDING SITE FOR RESIDUE FMN A 218 source : AC1 3) chain B residue 40 type sequence S description BINDING SITE FOR RESIDUE FMN A 218 source : AC1 4) chain B residue 41 type sequence T description BINDING SITE FOR RESIDUE FMN A 218 source : AC1 5) chain B residue 42 type sequence N description BINDING SITE FOR RESIDUE FMN A 218 source : AC1 6) chain B residue 142 type sequence Q description BINDING SITE FOR RESIDUE FMN A 218 source : AC1 7) chain B residue 145 type sequence L description BINDING SITE FOR RESIDUE FMN A 218 source : AC1 8) chain B residue 14 type sequence K description BINDING SITE FOR RESIDUE SN2 A 219 source : AC2 9) chain B residue 74 type sequence K description BINDING SITE FOR RESIDUE SN2 A 219 source : AC2 10) chain B residue 10 type sequence R description BINDING SITE FOR RESIDUE FMN B 220 source : AC3 11) chain B residue 11 type sequence H description BINDING SITE FOR RESIDUE FMN B 220 source : AC3 12) chain B residue 12 type sequence S description BINDING SITE FOR RESIDUE FMN B 220 source : AC3 13) chain B residue 14 type sequence K description BINDING SITE FOR RESIDUE FMN B 220 source : AC3 14) chain B residue 74 type sequence K description BINDING SITE FOR RESIDUE FMN B 220 source : AC3 15) chain B residue 163 type sequence P description BINDING SITE FOR RESIDUE FMN B 220 source : AC3 16) chain B residue 164 type sequence I description BINDING SITE FOR RESIDUE FMN B 220 source : AC3 17) chain B residue 165 type sequence E description BINDING SITE FOR RESIDUE FMN B 220 source : AC3 18) chain B residue 166 type sequence G description BINDING SITE FOR RESIDUE FMN B 220 source : AC3 19) chain B residue 205 type sequence K description BINDING SITE FOR RESIDUE FMN B 220 source : AC3 20) chain B residue 207 type sequence R description BINDING SITE FOR RESIDUE FMN B 220 source : AC3 21) chain B residue 10 type BINDING sequence R description BINDING => ECO:0000269|PubMed:11020276, ECO:0000269|PubMed:11491290, ECO:0000269|PubMed:15684426 source Swiss-Prot : SWS_FT_FI1 22) chain B residue 165 type BINDING sequence E description BINDING => ECO:0000269|PubMed:11020276, ECO:0000269|PubMed:11491290, ECO:0000269|PubMed:15684426 source Swiss-Prot : SWS_FT_FI1 23) chain B residue 205 type BINDING sequence K description BINDING => ECO:0000269|PubMed:11020276, ECO:0000269|PubMed:11491290, ECO:0000269|PubMed:15684426 source Swiss-Prot : SWS_FT_FI1 24) chain B residue 14 type catalytic sequence K description 211 source MCSA : MCSA2 25) chain B residue 74 type catalytic sequence K description 211 source MCSA : MCSA2 26) chain B residue 165 type catalytic sequence E description 211 source MCSA : MCSA2 27) chain B residue 107 type BINDING sequence R description BINDING => ECO:0000250|UniProtKB:Q01234 source Swiss-Prot : SWS_FT_FI2 28) chain B residue 41 type BINDING sequence T description BINDING => ECO:0000250|UniProtKB:Q01234 source Swiss-Prot : SWS_FT_FI2 29) chain B residue 71 type BINDING sequence N description BINDING => ECO:0000250|UniProtKB:Q01234 source Swiss-Prot : SWS_FT_FI2 30) chain B residue 74 type BINDING sequence K description BINDING => ECO:0000250|UniProtKB:Q01234 source Swiss-Prot : SWS_FT_FI2 31) chain B residue 14 type BINDING sequence K description BINDING => ECO:0000250|UniProtKB:Q01234 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links