|
|
eF-site ID
|
1oiy-D |
|
PDB Code
|
1oiy |
|
Chain
|
D |
|
click to enlarge
|
|
|
Title
|
Structure of human Thr160-phospho CDK2/cyclin A complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor |
|
Classification
|
KINASE |
|
Compound
|
CELL DIVISION PROTEIN KINASE 2 |
|
Source
|
Homo sapiens (Human) (CGA2_HUMAN) |
|
|
Sequence
|
D: |
VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL
VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQ
LVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRM
EHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM
FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPE
SLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYK
NSKYHGVSLLNPPETLNL
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
D |
| residue |
189 |
| type |
|
| sequence |
M
|
| description |
BINDING SITE FOR RESIDUE SGM D1193
|
| source |
: AC5
|
|
|
2)
|
chain |
D |
| residue |
193 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE SGM D1193
|
| source |
: AC5
|
|
|
3)
|
chain |
D |
| residue |
241 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE SGM D1193
|
| source |
: AC5
|
|
|
4)
|
chain |
D |
| residue |
305 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE SGM D1193
|
| source |
: AC5
|
|
|
|