eF-site ID 1oiu-B PDB Code 1oiu Chain B click to enlarge Title Structure of human Thr160-phospho CDK2/cyclin A complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor Classification KINASE Compound CELL DIVISION PROTEIN KINASE 2 Source Homo sapiens (Human) (CGA2_HUMAN) Sequence B:  DYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVD WLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLV GTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEH LVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFL GELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESL IRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNS KYHGVSLLNPPETLNL Description Functional site 1) chain B residue 200 type sequence M description BINDING SITE FOR RESIDUE MG B1433 source : AC1 2) chain B residue 203 type sequence Q description BINDING SITE FOR RESIDUE MG B1433 source : AC1 3) chain B residue 206 type sequence I description BINDING SITE FOR RESIDUE MG B1433 source : AC1 4) chain B residue 189 type sequence M description BINDING SITE FOR RESIDUE SGM B1193 source : AC4 5) chain B residue 192 type sequence K description BINDING SITE FOR RESIDUE SGM B1193 source : AC4 6) chain B residue 193 type sequence C description BINDING SITE FOR RESIDUE SGM B1193 source : AC4 7) chain B residue 241 type sequence R description BINDING SITE FOR RESIDUE SGM B1193 source : AC4 8) chain B residue 305 type sequence D description BINDING SITE FOR RESIDUE SGM B1193 source : AC4 9) chain B residue 211-242 type prosite sequence RAILVDWLVEVGEEYKLQNETLHLAVNYIDRF description CYCLINS Cyclins signature. RaiLvdWLvevgeeykLqnetLhlAVnYIDRF source prosite : PS00292

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