eF-site ID 1ofn-B PDB Code 1ofn Chain B click to enlarge Title Purification, crystallisation and preliminary structural studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis; the fourth enzyme in the dTDP-L-epivancosamine biosynthetic pathway. Classification ISOMERASE Compound PCZA361.16 Source (O52806) Sequence B:  MQARKLAVDGAIEFTPRVFADDRGLLILPYQEEAFVEAHG GPLFRVAQTIHSMSKRGVVRGIHYTVTPPGTAKYVYCARG KAMDIVIDIRVGSPTFGQWDSVLMDQQDPRAVYLPVGVGH AFVALEDDTVMSYMLSRSYVTQDELALSALDPALGLPIDI GVEPIVSDRDRVAITLAEAQRQGLLPDYTTSQEIERRLTA VPV Description Functional site 1) chain B residue 60 type sequence R description BINDING SITE FOR RESIDUE GOL A1203 source : AC1 2) chain B residue 76 type sequence Y description BINDING SITE FOR RESIDUE GOL A1204 source : AC2 3) chain B residue 132 type sequence S description BINDING SITE FOR RESIDUE GOL A1204 source : AC2 4) chain B residue 134 type sequence M description BINDING SITE FOR RESIDUE GOL A1204 source : AC2 5) chain B residue 50 type sequence I description BINDING SITE FOR RESIDUE GOL B1203 source : AC4 6) chain B residue 63 type sequence H description BINDING SITE FOR RESIDUE GOL B1203 source : AC4 7) chain B residue 73 type sequence K description BINDING SITE FOR RESIDUE GOL B1203 source : AC4 8) chain B residue 120 type sequence H description BINDING SITE FOR RESIDUE GOL B1203 source : AC4 9) chain B residue 133 type sequence Y description BINDING SITE FOR RESIDUE GOL B1203 source : AC4

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