eF-site ID 1o9s-L
PDB Code 1o9s
Chain L

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Title Crystal structure of a ternary complex of the human histone methyltransferase SET7/9
Classification TRANSFERASE
Compound HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC
Source null (Q16776)
Sequence L:  ARTXQT
Description


Functional site

1) chain L
residue 4
type
sequence X
description BINDING SITE FOR RESIDUE SAH B1367
source : AC2

2) chain L
residue 5
type MOD_RES
sequence Q
description 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594
source Swiss-Prot : SWS_FT_FI4

3) chain L
residue 6
type MOD_RES
sequence T
description Phosphothreonine; by PKC => ECO:0000269|PubMed:20228790
source Swiss-Prot : SWS_FT_FI5

4) chain L
residue 2
type MOD_RES
sequence R
description Citrulline; alternate => ECO:0000269|PubMed:16567635
source Swiss-Prot : SWS_FT_FI1

5) chain L
residue 3
type MOD_RES
sequence T
description Phosphothreonine; by HASPIN => ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088
source Swiss-Prot : SWS_FT_FI2

6) chain L
residue 4
type MOD_RES
sequence X
description N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708
source Swiss-Prot : SWS_FT_FI3


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