eF-site ID 1nyx-AB PDB Code 1nyx Chain A, B click to enlarge Title Ligand binding domain of the human peroxisome proliferator activated receptor gamma in complex with an agonist Classification TRANSCRIPTION Compound peroxisome proliferator activated receptor gamma Source null (PPAT_HUMAN) Sequence A:  DQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKT TDKSPFVIYDMNSLMMGEDKVAIRIFQGCQFRSVEAVQEI TEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNK DGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNA LELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQA LELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVI KKTETDMSLHPLLQEIYKDL B:  ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSP FVIYDMNSLMMGEDKIKFKHITVAIRIFQGCQFRSVEAVQ EITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLM NKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKF NALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLL QALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQ VIKKTETHPLLQEIYKDL Description Functional site 1) chain A residue 281 type sequence I description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 2) chain A residue 282 type sequence F description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 3) chain A residue 285 type sequence C description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 4) chain A residue 286 type sequence Q description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 5) chain A residue 288 type sequence R description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 6) chain A residue 289 type sequence S description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 7) chain A residue 323 type sequence H description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 8) chain A residue 326 type sequence I description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 9) chain A residue 330 type sequence L description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 10) chain A residue 340 type sequence L description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 11) chain A residue 342 type sequence S description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 12) chain A residue 449 type sequence H description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 13) chain A residue 469 type sequence L description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 14) chain A residue 473 type sequence Y description BINDING SITE FOR RESIDUE DRF A 101 source : AC1 15) chain A residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 16) chain A residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 17) chain A residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 18) chain A residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 19) chain B residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 20) chain B residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 21) chain B residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 22) chain B residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 23) chain A residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2 24) chain B residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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