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|
eF-site ID
|
1nyu-ABCD |
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PDB Code
|
1nyu |
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Chain
|
A, B, C, D |
|
click to enlarge
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Title
|
Crystal Structure of Activin A Bound to the ECD of ActRIIB |
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Classification
|
MEMBRANE PROTEIN/HORMONE/GROWTH FACTOR |
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Compound
|
activin receptor |
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Source
|
Rattus norvegicus (Rat) (INHBA_HUMAN) |
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Sequence
|
A: |
TRECIYYNANWELERTNQSLERCEGEQDKRLHCYASWRNS
SGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEG
NFCNERFTHLPE
|
| B: |
LECDGKVICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEG
ECPSHILKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIV
EECGCS
|
| C: |
TRECIYYNANWLERTNQSGLERCEGEQDKRLHCYASWTIE
LVKKGCWLDFNCYECVATEENPQVYFCCCEGNFCNERFTH
LPE
|
| D: |
CCKKFFVSIIAPSGYHNYCEGECPCCVPTKLRPMSMLYYD
DGIIKKDIQNMIVEECGCS
|
|
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
42 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
65 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
C |
| residue |
42 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
B |
| residue |
29-44 |
| type |
prosite |
| sequence |
IIAPSGYHANYCEGEC
|
| description |
TGF_BETA_1 TGF-beta family signature. IiaPsgYhanyCeGeC
|
| source |
prosite : PS00250
|
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