|
eF-site ID
|
1nyj-D |
PDB Code
|
1nyj |
Chain
|
D |
|
click to enlarge
|
|
Title
|
The closed state structure of M2 protein H+ channel by solid state NMR spectroscopy |
Classification
|
VIRAL PROTEIN |
Compound
|
Matrix protein M2 |
Source
|
Influenza A virus (strain A/USSR/90/1977 H1N1) (VMT2_IAUSS) |
|
Sequence
|
D: |
SSDPLVVAASIIGILHLILWILDRL
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
D |
residue |
2-22 |
type |
TRANSMEM |
sequence |
SDPLVVAASIIGILHLILWIL
|
description |
Helical; Signal-anchor for type III membrane protein => ECO:0000255|HAMAP-Rule:MF_04069
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
2)
|
chain |
D |
residue |
16 |
type |
SITE |
sequence |
H
|
description |
Essential for channel activity, possibly by being protonated during channel activation, and by forming the channel gate and the selective filter => ECO:0000255|HAMAP-Rule:MF_04069
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
3)
|
chain |
D |
residue |
20 |
type |
SITE |
sequence |
W
|
description |
Seems to be involved in pH gating => ECO:0000255|HAMAP-Rule:MF_04069
|
source |
Swiss-Prot : SWS_FT_FI3
|
|
|
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