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eF-site ID
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1nyj-B |
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PDB Code
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1nyj |
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Chain
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B |
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click to enlarge
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Title
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The closed state structure of M2 protein H+ channel by solid state NMR spectroscopy |
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Classification
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VIRAL PROTEIN |
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Compound
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Matrix protein M2 |
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Source
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Influenza A virus (strain A/USSR/90/1977 H1N1) (VMT2_IAUSS) |
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Sequence
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B: |
SSDPLVVAASIIGILHLILWILDRL
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Description
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Functional site
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1)
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chain |
B |
| residue |
2-22 |
| type |
TRANSMEM |
| sequence |
SDPLVVAASIIGILHLILWIL
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| description |
Helical; Signal-anchor for type III membrane protein => ECO:0000255|HAMAP-Rule:MF_04069
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
B |
| residue |
16 |
| type |
SITE |
| sequence |
H
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| description |
Essential for channel activity, possibly by being protonated during channel activation, and by forming the channel gate and the selective filter => ECO:0000255|HAMAP-Rule:MF_04069
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| source |
Swiss-Prot : SWS_FT_FI2
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3)
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chain |
B |
| residue |
20 |
| type |
SITE |
| sequence |
W
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| description |
Seems to be involved in pH gating => ECO:0000255|HAMAP-Rule:MF_04069
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| source |
Swiss-Prot : SWS_FT_FI3
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