eF-site ID 1nw4-F PDB Code 1nw4 Chain F click to enlarge Title Crystal Structure of Plasmodium falciparum Purine Nucleoside Phosphorylase in complex with ImmH and Sulfate Classification TRANSFERASE Compound uridine phosphorylase, putative Source Plasmodium falciparum (isolate 3D7) (Q8I3X4_PLAF7) Sequence F:  NLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLA YNREYKSVECHYKGQKFLCVSHGVGSAGCAVCFEELCQNG AKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHLLI HGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYP NKIIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGGI LIVDGCPFKWDEGDFDNNLVPHQLENMIKIALGACAKLAT KYA Description Functional site 1) chain F residue 45 type sequence R description BINDING SITE FOR RESIDUE SO4 E 405 source : AC5 2) chain F residue 23 type sequence G description BINDING SITE FOR RESIDUE SO4 F 406 source : AC6 3) chain F residue 88 type sequence R description BINDING SITE FOR RESIDUE SO4 F 406 source : AC6 4) chain F residue 90 type sequence G description BINDING SITE FOR RESIDUE SO4 F 406 source : AC6 5) chain F residue 91 type sequence S description BINDING SITE FOR RESIDUE SO4 F 406 source : AC6 6) chain F residue 123 type sequence H description BINDING SITE FOR RESIDUE SO4 F 409 source : AC9 7) chain F residue 124 type sequence G description BINDING SITE FOR RESIDUE SO4 F 409 source : AC9 8) chain F residue 125 type sequence D description BINDING SITE FOR RESIDUE SO4 F 409 source : AC9 9) chain F residue 169 type sequence R description BINDING SITE FOR RESIDUE SO4 A 413 source : BC4 10) chain F residue 101 type sequence K description BINDING SITE FOR RESIDUE SO4 F 414 source : BC5 11) chain F residue 102 type sequence R description BINDING SITE FOR RESIDUE SO4 F 414 source : BC5 12) chain F residue 216 type sequence D description BINDING SITE FOR RESIDUE SO4 F 414 source : BC5 13) chain F residue 27 type sequence R description BINDING SITE FOR RESIDUE SO4 F 415 source : BC6 14) chain F residue 220 type sequence N description BINDING SITE FOR RESIDUE SO4 F 415 source : BC6 15) chain F residue 221 type sequence L description BINDING SITE FOR RESIDUE SO4 F 415 source : BC6 16) chain F residue 7 type sequence H description BINDING SITE FOR RESIDUE IMH E 305 source : CC6 17) chain F residue 88 type sequence R description BINDING SITE FOR RESIDUE IMH F 306 source : CC7 18) chain F residue 91 type sequence S description BINDING SITE FOR RESIDUE IMH F 306 source : CC7 19) chain F residue 92 type sequence C description BINDING SITE FOR RESIDUE IMH F 306 source : CC7 20) chain F residue 93 type sequence G description BINDING SITE FOR RESIDUE IMH F 306 source : CC7 21) chain F residue 182 type sequence E description BINDING SITE FOR RESIDUE IMH F 306 source : CC7 22) chain F residue 183 type sequence M description BINDING SITE FOR RESIDUE IMH F 306 source : CC7 23) chain F residue 184 type sequence E description BINDING SITE FOR RESIDUE IMH F 306 source : CC7 24) chain F residue 206 type sequence D description BINDING SITE FOR RESIDUE IMH F 306 source : CC7 25) chain F residue 212 type sequence W description BINDING SITE FOR RESIDUE IMH F 306 source : CC7 26) chain F residue 44 type sequence N description BINDING SITE FOR RESIDUE IPA F 505 source : DC3 27) chain F residue 45 type sequence R description BINDING SITE FOR RESIDUE IPA F 505 source : DC3 28) chain F residue 169 type sequence R description BINDING SITE FOR RESIDUE IPA A 510 source : DC8 29) chain F residue 116 type sequence R description BINDING SITE FOR RESIDUE IPA F 511 source : DC9 30) chain F residue 119 type sequence H description BINDING SITE FOR RESIDUE IPA F 511 source : DC9 31) chain F residue 120 type sequence L description BINDING SITE FOR RESIDUE IPA F 511 source : DC9 32) chain F residue 119 type sequence H description BINDING SITE FOR RESIDUE IPA F 512 source : EC1 33) chain F residue 123 type sequence H description BINDING SITE FOR RESIDUE IPA F 512 source : EC1 34) chain F residue 27 type catalytic sequence R description 695 source MCSA : MCSA6 35) chain F residue 45 type catalytic sequence R description 695 source MCSA : MCSA6 36) chain F residue 88 type catalytic sequence R description 695 source MCSA : MCSA6 37) chain F residue 206 type catalytic sequence D description 695 source MCSA : MCSA6 38) chain F residue 206 type ACT_SITE sequence D description Proton donor => ECO:0000305|PubMed:24416224 source Swiss-Prot : SWS_FT_FI1 39) chain F residue 7 type BINDING sequence H description BINDING => ECO:0000305|PubMed:24416224, ECO:0000305|Ref.7, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI2 40) chain F residue 23 type BINDING sequence G description in other chain => ECO:0000269|PubMed:24416224, ECO:0000269|Ref.7, ECO:0000305|PubMed:14982926, ECO:0000305|PubMed:19575810, ECO:0007744|PDB:1NW4, ECO:0007744|PDB:1Q1G, ECO:0007744|PDB:3ENZ, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI3 41) chain F residue 45 type BINDING sequence R description BINDING => ECO:0000269|PubMed:24416224, ECO:0000269|Ref.7, ECO:0000305|PubMed:14982926, ECO:0000305|PubMed:19575810, ECO:0007744|PDB:1NW4, ECO:0007744|PDB:1Q1G, ECO:0007744|PDB:3ENZ, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI4 42) chain F residue 88 type BINDING sequence R description in other chain => ECO:0000269|PubMed:24416224, ECO:0000269|PubMed:29440412, ECO:0000269|Ref.7, ECO:0000305|PubMed:14982926, ECO:0000305|PubMed:19575810, ECO:0007744|PDB:1NW4, ECO:0007744|PDB:1Q1G, ECO:0007744|PDB:3ENZ, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC, ECO:0007744|PDB:6AQS, ECO:0007744|PDB:6AQU source Swiss-Prot : SWS_FT_FI5 43) chain F residue 183 type BINDING sequence M description in other chain => ECO:0000269|PubMed:16131758, ECO:0000305|PubMed:24416224, ECO:0000305|Ref.7, ECO:0007744|PDB:2BSX, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI6

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