eF-site ID 1nw4-D PDB Code 1nw4 Chain D click to enlarge Title Crystal Structure of Plasmodium falciparum Purine Nucleoside Phosphorylase in complex with ImmH and Sulfate Classification TRANSFERASE Compound uridine phosphorylase, putative Source null (Q8I3X4_PLAF7) Sequence D:  NLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLA YNREYKSVECHYKGQKFLCVSHGVGSAGCAVCFEELCQNG AKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHLLI HGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYP NKIIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGGI LIVDGCPFKWDEGDFDNNLVPHQLENMIKIALGACAKLAT KYA Description Functional site 1) chain D residue 45 type sequence R description BINDING SITE FOR RESIDUE SO4 C 403 source : AC3 2) chain D residue 23 type sequence G description BINDING SITE FOR RESIDUE SO4 D 404 source : AC4 3) chain D residue 88 type sequence R description BINDING SITE FOR RESIDUE SO4 D 404 source : AC4 4) chain D residue 89 type sequence A description BINDING SITE FOR RESIDUE SO4 D 404 source : AC4 5) chain D residue 90 type sequence G description BINDING SITE FOR RESIDUE SO4 D 404 source : AC4 6) chain D residue 91 type sequence S description BINDING SITE FOR RESIDUE SO4 D 404 source : AC4 7) chain D residue 123 type sequence H description BINDING SITE FOR RESIDUE SO4 D 408 source : AC8 8) chain D residue 124 type sequence G description BINDING SITE FOR RESIDUE SO4 D 408 source : AC8 9) chain D residue 125 type sequence D description BINDING SITE FOR RESIDUE SO4 D 408 source : AC8 10) chain D residue 223 type sequence P description BINDING SITE FOR RESIDUE SO4 A 412 source : BC3 11) chain D residue 169 type sequence R description BINDING SITE FOR RESIDUE SO4 E 416 source : BC7 12) chain D residue 101 type sequence K description BINDING SITE FOR RESIDUE SO4 D 417 source : BC8 13) chain D residue 102 type sequence R description BINDING SITE FOR RESIDUE SO4 D 417 source : BC8 14) chain D residue 216 type sequence D description BINDING SITE FOR RESIDUE SO4 D 417 source : BC8 15) chain D residue 7 type sequence H description BINDING SITE FOR RESIDUE IMH C 303 source : CC4 16) chain D residue 88 type sequence R description BINDING SITE FOR RESIDUE IMH D 304 source : CC5 17) chain D residue 91 type sequence S description BINDING SITE FOR RESIDUE IMH D 304 source : CC5 18) chain D residue 92 type sequence C description BINDING SITE FOR RESIDUE IMH D 304 source : CC5 19) chain D residue 93 type sequence G description BINDING SITE FOR RESIDUE IMH D 304 source : CC5 20) chain D residue 160 type sequence Y description BINDING SITE FOR RESIDUE IMH D 304 source : CC5 21) chain D residue 181 type sequence V description BINDING SITE FOR RESIDUE IMH D 304 source : CC5 22) chain D residue 182 type sequence E description BINDING SITE FOR RESIDUE IMH D 304 source : CC5 23) chain D residue 183 type sequence M description BINDING SITE FOR RESIDUE IMH D 304 source : CC5 24) chain D residue 184 type sequence E description BINDING SITE FOR RESIDUE IMH D 304 source : CC5 25) chain D residue 206 type sequence D description BINDING SITE FOR RESIDUE IMH D 304 source : CC5 26) chain D residue 212 type sequence W description BINDING SITE FOR RESIDUE IMH D 304 source : CC5 27) chain D residue 6 type sequence R description BINDING SITE FOR RESIDUE IPA D 503 source : DC1 28) chain D residue 45 type sequence R description BINDING SITE FOR RESIDUE IPA D 503 source : DC1 29) chain D residue 169 type sequence R description BINDING SITE FOR RESIDUE IPA E 513 source : EC2 30) chain D residue 119 type sequence H description BINDING SITE FOR RESIDUE IPA D 514 source : EC3 31) chain D residue 123 type sequence H description BINDING SITE FOR RESIDUE IPA D 514 source : EC3 32) chain D residue 206 type ACT_SITE sequence D description Proton donor => ECO:0000305|PubMed:24416224 source Swiss-Prot : SWS_FT_FI1 33) chain D residue 7 type BINDING sequence H description BINDING => ECO:0000305|PubMed:24416224, ECO:0000305|Ref.7, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI2 34) chain D residue 23 type BINDING sequence G description in other chain => ECO:0000269|PubMed:24416224, ECO:0000269|Ref.7, ECO:0000305|PubMed:14982926, ECO:0000305|PubMed:19575810, ECO:0007744|PDB:1NW4, ECO:0007744|PDB:1Q1G, ECO:0007744|PDB:3ENZ, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI3 35) chain D residue 27 type catalytic sequence R description 695 source MCSA : MCSA4 36) chain D residue 45 type catalytic sequence R description 695 source MCSA : MCSA4 37) chain D residue 88 type catalytic sequence R description 695 source MCSA : MCSA4 38) chain D residue 206 type catalytic sequence D description 695 source MCSA : MCSA4 39) chain D residue 45 type BINDING sequence R description BINDING => ECO:0000269|PubMed:24416224, ECO:0000269|Ref.7, ECO:0000305|PubMed:14982926, ECO:0000305|PubMed:19575810, ECO:0007744|PDB:1NW4, ECO:0007744|PDB:1Q1G, ECO:0007744|PDB:3ENZ, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI4 40) chain D residue 88 type BINDING sequence R description in other chain => ECO:0000269|PubMed:24416224, ECO:0000269|PubMed:29440412, ECO:0000269|Ref.7, ECO:0000305|PubMed:14982926, ECO:0000305|PubMed:19575810, ECO:0007744|PDB:1NW4, ECO:0007744|PDB:1Q1G, ECO:0007744|PDB:3ENZ, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC, ECO:0007744|PDB:6AQS, ECO:0007744|PDB:6AQU source Swiss-Prot : SWS_FT_FI5 41) chain D residue 183 type BINDING sequence M description in other chain => ECO:0000269|PubMed:16131758, ECO:0000305|PubMed:24416224, ECO:0000305|Ref.7, ECO:0007744|PDB:2BSX, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI6

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