eF-site ID 1nw4-C PDB Code 1nw4 Chain C click to enlarge Title Crystal Structure of Plasmodium falciparum Purine Nucleoside Phosphorylase in complex with ImmH and Sulfate Classification TRANSFERASE Compound uridine phosphorylase, putative Source Plasmodium falciparum (isolate 3D7) (Q8I3X4_PLAF7) Sequence C:  NLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLA YNREYKSVECHYKGQKFLCVSHGVGSAGCAVCFEELCQNG AKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHLLI HGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYP NKIIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGGI LIVDGCPFKWDEGDFDNNLVPHQLENMIKIALGACAKLAT KYA Description Functional site 1) chain C residue 23 type sequence G description BINDING SITE FOR RESIDUE SO4 C 403 source : AC3 2) chain C residue 88 type sequence R description BINDING SITE FOR RESIDUE SO4 C 403 source : AC3 3) chain C residue 90 type sequence G description BINDING SITE FOR RESIDUE SO4 C 403 source : AC3 4) chain C residue 91 type sequence S description BINDING SITE FOR RESIDUE SO4 C 403 source : AC3 5) chain C residue 45 type sequence R description BINDING SITE FOR RESIDUE SO4 D 404 source : AC4 6) chain C residue 169 type sequence R description BINDING SITE FOR RESIDUE SO4 B 407 source : AC7 7) chain C residue 123 type sequence H description BINDING SITE FOR RESIDUE SO4 C 418 source : BC9 8) chain C residue 124 type sequence G description BINDING SITE FOR RESIDUE SO4 C 418 source : BC9 9) chain C residue 125 type sequence D description BINDING SITE FOR RESIDUE SO4 C 418 source : BC9 10) chain C residue 88 type sequence R description BINDING SITE FOR RESIDUE IMH C 303 source : CC4 11) chain C residue 91 type sequence S description BINDING SITE FOR RESIDUE IMH C 303 source : CC4 12) chain C residue 92 type sequence C description BINDING SITE FOR RESIDUE IMH C 303 source : CC4 13) chain C residue 93 type sequence G description BINDING SITE FOR RESIDUE IMH C 303 source : CC4 14) chain C residue 160 type sequence Y description BINDING SITE FOR RESIDUE IMH C 303 source : CC4 15) chain C residue 182 type sequence E description BINDING SITE FOR RESIDUE IMH C 303 source : CC4 16) chain C residue 183 type sequence M description BINDING SITE FOR RESIDUE IMH C 303 source : CC4 17) chain C residue 184 type sequence E description BINDING SITE FOR RESIDUE IMH C 303 source : CC4 18) chain C residue 206 type sequence D description BINDING SITE FOR RESIDUE IMH C 303 source : CC4 19) chain C residue 212 type sequence W description BINDING SITE FOR RESIDUE IMH C 303 source : CC4 20) chain C residue 7 type sequence H description BINDING SITE FOR RESIDUE IMH D 304 source : CC5 21) chain C residue 6 type sequence R description BINDING SITE FOR RESIDUE IPA C 504 source : DC2 22) chain C residue 44 type sequence N description BINDING SITE FOR RESIDUE IPA C 504 source : DC2 23) chain C residue 45 type sequence R description BINDING SITE FOR RESIDUE IPA C 504 source : DC2 24) chain C residue 169 type sequence R description BINDING SITE FOR RESIDUE IPA B 508 source : DC6 25) chain C residue 119 type sequence H description BINDING SITE FOR RESIDUE IPA B 515 source : EC4 26) chain C residue 123 type sequence H description BINDING SITE FOR RESIDUE IPA B 515 source : EC4 27) chain C residue 25 type catalytic sequence P description 695 source MCSA : MCSA3 28) chain C residue 43 type catalytic sequence Y description 695 source MCSA : MCSA3 29) chain C residue 86 type catalytic sequence I description 695 source MCSA : MCSA3 30) chain C residue 204 type catalytic sequence I description 695 source MCSA : MCSA3 31) chain C residue 43 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:24416224, ECO:0000269|Ref.7, ECO:0000305|PubMed:14982926, ECO:0000305|PubMed:19575810, ECO:0007744|PDB:1NW4, ECO:0007744|PDB:1Q1G, ECO:0007744|PDB:3ENZ, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI4 32) chain C residue 86 type BINDING sequence I description in other chain => ECO:0000269|PubMed:24416224, ECO:0000269|PubMed:29440412, ECO:0000269|Ref.7, ECO:0000305|PubMed:14982926, ECO:0000305|PubMed:19575810, ECO:0007744|PDB:1NW4, ECO:0007744|PDB:1Q1G, ECO:0007744|PDB:3ENZ, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC, ECO:0007744|PDB:6AQS, ECO:0007744|PDB:6AQU source Swiss-Prot : SWS_FT_FI5 33) chain C residue 181 type BINDING sequence V description in other chain => ECO:0000269|PubMed:16131758, ECO:0000305|PubMed:24416224, ECO:0000305|Ref.7, ECO:0007744|PDB:2BSX, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI6 34) chain C residue 5 type BINDING sequence L description BINDING => ECO:0000305|PubMed:24416224, ECO:0000305|Ref.7, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI2 35) chain C residue 21 type BINDING sequence V description in other chain => ECO:0000269|PubMed:24416224, ECO:0000269|Ref.7, ECO:0000305|PubMed:14982926, ECO:0000305|PubMed:19575810, ECO:0007744|PDB:1NW4, ECO:0007744|PDB:1Q1G, ECO:0007744|PDB:3ENZ, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI3 36) chain C residue 204 type ACT_SITE sequence I description Proton donor => ECO:0000305|PubMed:24416224 source Swiss-Prot : SWS_FT_FI1

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