eF-site ID 1nw4-A PDB Code 1nw4 Chain A click to enlarge Title Crystal Structure of Plasmodium falciparum Purine Nucleoside Phosphorylase in complex with ImmH and Sulfate Classification TRANSFERASE Compound uridine phosphorylase, putative Source null (Q8I3X4_PLAF7) Sequence A:  NLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLA YNREYKSVECHYKGQKFLCVSHGVGSAGCAVCFEELCQNG AKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHLLI HGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYP NKIIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGGI LIVDGCPFKWDEGDFDNNLVPHQLENMIKIALGACAKLAT KYA Description Functional site 1) chain A residue 23 type sequence G description BINDING SITE FOR RESIDUE SO4 A 401 source : AC1 2) chain A residue 88 type sequence R description BINDING SITE FOR RESIDUE SO4 A 401 source : AC1 3) chain A residue 90 type sequence G description BINDING SITE FOR RESIDUE SO4 A 401 source : AC1 4) chain A residue 91 type sequence S description BINDING SITE FOR RESIDUE SO4 A 401 source : AC1 5) chain A residue 45 type sequence R description BINDING SITE FOR RESIDUE SO4 B 402 source : AC2 6) chain A residue 169 type sequence R description BINDING SITE FOR RESIDUE SO4 F 409 source : AC9 7) chain A residue 218 type sequence D description BINDING SITE FOR RESIDUE SO4 A 411 source : BC2 8) chain A residue 219 type sequence N description BINDING SITE FOR RESIDUE SO4 A 411 source : BC2 9) chain A residue 220 type sequence N description BINDING SITE FOR RESIDUE SO4 A 411 source : BC2 10) chain A residue 101 type sequence K description BINDING SITE FOR RESIDUE SO4 A 412 source : BC3 11) chain A residue 102 type sequence R description BINDING SITE FOR RESIDUE SO4 A 412 source : BC3 12) chain A residue 216 type sequence D description BINDING SITE FOR RESIDUE SO4 A 412 source : BC3 13) chain A residue 123 type sequence H description BINDING SITE FOR RESIDUE SO4 A 413 source : BC4 14) chain A residue 124 type sequence G description BINDING SITE FOR RESIDUE SO4 A 413 source : BC4 15) chain A residue 125 type sequence D description BINDING SITE FOR RESIDUE SO4 A 413 source : BC4 16) chain A residue 224 type sequence H description BINDING SITE FOR RESIDUE SO4 D 417 source : BC8 17) chain A residue 88 type sequence R description BINDING SITE FOR RESIDUE IMH A 301 source : CC2 18) chain A residue 91 type sequence S description BINDING SITE FOR RESIDUE IMH A 301 source : CC2 19) chain A residue 92 type sequence C description BINDING SITE FOR RESIDUE IMH A 301 source : CC2 20) chain A residue 93 type sequence G description BINDING SITE FOR RESIDUE IMH A 301 source : CC2 21) chain A residue 160 type sequence Y description BINDING SITE FOR RESIDUE IMH A 301 source : CC2 22) chain A residue 182 type sequence E description BINDING SITE FOR RESIDUE IMH A 301 source : CC2 23) chain A residue 183 type sequence M description BINDING SITE FOR RESIDUE IMH A 301 source : CC2 24) chain A residue 184 type sequence E description BINDING SITE FOR RESIDUE IMH A 301 source : CC2 25) chain A residue 206 type sequence D description BINDING SITE FOR RESIDUE IMH A 301 source : CC2 26) chain A residue 212 type sequence W description BINDING SITE FOR RESIDUE IMH A 301 source : CC2 27) chain A residue 7 type sequence H description BINDING SITE FOR RESIDUE IMH B 302 source : CC3 28) chain A residue 6 type sequence R description BINDING SITE FOR RESIDUE IPA A 502 source : CC9 29) chain A residue 44 type sequence N description BINDING SITE FOR RESIDUE IPA A 502 source : CC9 30) chain A residue 45 type sequence R description BINDING SITE FOR RESIDUE IPA A 502 source : CC9 31) chain A residue 169 type sequence R description BINDING SITE FOR RESIDUE IPA B 507 source : DC5 32) chain A residue 116 type sequence R description BINDING SITE FOR RESIDUE IPA A 509 source : DC7 33) chain A residue 119 type sequence H description BINDING SITE FOR RESIDUE IPA A 509 source : DC7 34) chain A residue 119 type sequence H description BINDING SITE FOR RESIDUE IPA A 510 source : DC8 35) chain A residue 123 type sequence H description BINDING SITE FOR RESIDUE IPA A 510 source : DC8 36) chain A residue 169 type sequence R description BINDING SITE FOR RESIDUE IPA F 512 source : EC1 37) chain A residue 206 type ACT_SITE sequence D description Proton donor => ECO:0000305|PubMed:24416224 source Swiss-Prot : SWS_FT_FI1 38) chain A residue 7 type BINDING sequence H description BINDING => ECO:0000305|PubMed:24416224, ECO:0000305|Ref.7, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI2 39) chain A residue 23 type BINDING sequence G description in other chain => ECO:0000269|PubMed:24416224, ECO:0000269|Ref.7, ECO:0000305|PubMed:14982926, ECO:0000305|PubMed:19575810, ECO:0007744|PDB:1NW4, ECO:0007744|PDB:1Q1G, ECO:0007744|PDB:3ENZ, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI3 40) chain A residue 27 type catalytic sequence R description 695 source MCSA : MCSA1 41) chain A residue 45 type catalytic sequence R description 695 source MCSA : MCSA1 42) chain A residue 88 type catalytic sequence R description 695 source MCSA : MCSA1 43) chain A residue 206 type catalytic sequence D description 695 source MCSA : MCSA1 44) chain A residue 45 type BINDING sequence R description BINDING => ECO:0000269|PubMed:24416224, ECO:0000269|Ref.7, ECO:0000305|PubMed:14982926, ECO:0000305|PubMed:19575810, ECO:0007744|PDB:1NW4, ECO:0007744|PDB:1Q1G, ECO:0007744|PDB:3ENZ, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI4 45) chain A residue 88 type BINDING sequence R description in other chain => ECO:0000269|PubMed:24416224, ECO:0000269|PubMed:29440412, ECO:0000269|Ref.7, ECO:0000305|PubMed:14982926, ECO:0000305|PubMed:19575810, ECO:0007744|PDB:1NW4, ECO:0007744|PDB:1Q1G, ECO:0007744|PDB:3ENZ, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC, ECO:0007744|PDB:6AQS, ECO:0007744|PDB:6AQU source Swiss-Prot : SWS_FT_FI5 46) chain A residue 183 type BINDING sequence M description in other chain => ECO:0000269|PubMed:16131758, ECO:0000305|PubMed:24416224, ECO:0000305|Ref.7, ECO:0007744|PDB:2BSX, ECO:0007744|PDB:3FOW, ECO:0007744|PDB:3PHC source Swiss-Prot : SWS_FT_FI6

Display surface Download Links