eF-site ID 1nu9-D PDB Code 1nu9 Chain D click to enlarge Title Staphylocoagulase-Prethrombin-2 complex Classification HYDROLASE/HYDROLASE INHIBITOR Compound Thrombin light and heavy chains Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; Sequence D:  GEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAE IGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYP PWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHP RYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAAS LLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIV ERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGP FVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKK WIQKVIDQFG Description (1)  Thrombin light and heavy chains (E.C.3.4.21.5)/Staphylocoagulase Functional site 1) chain D residue 57 type sequence H description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 2) chain D residue 60 type sequence L description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 3) chain D residue 99 type sequence L description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 4) chain D residue 189 type sequence D description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 5) chain D residue 190 type sequence A description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 6) chain D residue 193 type sequence G description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 7) chain D residue 194 type sequence D description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 8) chain D residue 195 type sequence S description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 9) chain D residue 214 type sequence S description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 10) chain D residue 215 type sequence W description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 11) chain D residue 216 type sequence G description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 12) chain D residue 219 type sequence G description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 13) chain D residue 226 type sequence G description BINDING SITE FOR RESIDUE 0ZJ D 299 source : AC2 14) chain D residue 57 type ACT_SITE sequence H description Charge relay system source Swiss-Prot : SWS_FT_FI1 15) chain D residue 102 type ACT_SITE sequence D description Charge relay system source Swiss-Prot : SWS_FT_FI1 16) chain D residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1 17) chain D residue 15 type SITE sequence R description Cleavage; by factor Xa => ECO:0000269|PubMed:34265300 source Swiss-Prot : SWS_FT_FI2 18) chain D residue 60 type CARBOHYD sequence L description N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19838169, ECO:0000269|PubMed:873923 source Swiss-Prot : SWS_FT_FI3

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