|
|
eF-site ID
|
1nn6-A |
|
PDB Code
|
1nn6 |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
Human Pro-Chymase |
|
Classification
|
HYDROLASE |
|
Compound
|
Chymase |
|
Source
|
(MCT1_HUMAN) |
|
|
Sequence
|
A: |
GGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLT
AAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYN
TSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRM
CRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDH
NLQLCVGNPRKTAFKGDSGGPLLCAGVAQGIVSYGRSDAK
PPAVFTRISHYRPWINQILQAN
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
56-61 |
| type |
prosite |
| sequence |
LTAAHC
|
| description |
TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC
|
| source |
prosite : PS00134
|
|
|
2)
|
chain |
A |
| residue |
60 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Charge relay system
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
104 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
Charge relay system
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
197 |
| type |
ACT_SITE |
| sequence |
S
|
| description |
Charge relay system
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
A |
| residue |
74 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:2071582
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
6)
|
chain |
A |
| residue |
97 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|