eF-site ID 1nmt-ABC PDB Code 1nmt Chain A, B, C click to enlarge Title N-MYRISTOYL TRANSFERASE FROM CANDIDA ALBICANS AT 2.45 A Classification MYRISTYLATION Compound N-MYRISTOYL TRANSFERASE Source Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (NMT_CANAL) Sequence A:  EGPIDKLKTPEDVPNDPLPLISDFEWSTLDIDDNLQLDEL YKLLYDNYVEDIDATFRFKYSHEFFQWALKPPGWRKDWHV GVRVKSTGKLVAFIAATPVTFKLNKSNKVIDSVEINFLCI HKKLRNKRLAPVLIKEITRRVNKQNIWQALYTGGSILPTP LTTCRYQHRPINWSKLHDVGFSHLPPNQTKSSMVASYTLP NNPKLKGLRPMTGKDVSTVLSLLYKYQERFDIVQLFTEEE FKHWMLGHDENSDSNVVKSYVVEDENGIITDYFSYYLLPF TVLDNAQHDELGIAYLFYYASDSFEKPNYKKRLNELITDA LITSKKFGVDVFNCLTCQDNTYFLKDCKFGSGDGFLNYYL FNYRTFPMDGGIDKKTKEVVEDQTSGIGVVLL B:  EGPIDKLKTPEDVPNDPLPLISDFEWSTLDIDDNLQLDEL YKLLYDNYVEDIDATFRFKYSHEFFQWALKPPGWRKDWHV GVRVKSTGKLVAFIAATPVTFKLNKSNKVIDSVEINFLCI HKKLRNKRLAPVLIKEITRRVNKQNIWQALYTGGSILPTP LTTCRYQHRPINWSKLHDVGFSHLPPNQTKSSMVASYTLP NNPKLKGLRPMTGKDVSTVLSLLYKYQERFDIVQLFTEEE FKHWMLGHDENSDSNVVKSYVVEDENGIITDYFSYYLLPF TVLDNAQHDELGIAYLFYYASDSFEKPNYKKRLNELITDA LITSKKFGVDVFNCLTCQDNTYFLKDCKFGSGDGFLNYYL FNYRTFPMDGGIDKKTKEVVEDQTSGIGVVLL C:  EGPIDKLKTPEDVPNDPLPLISDFEWSTLDIDDNLQLDEL YKLLYDNYVDATFRFKYSHEFFQWALKPPGWRKDWHVGVR VKSTGKLVAFIAATPVTFKLNKSNKVIDSVEINFLCIHKK LRNKRLAPVLIKEITRRVNKQNIWQALYTGGSILPTPLTT CRYQHRPINWSKLHDVGFSHLPPNQTKSSMVASYTLPNNP KLKGLRPMTGKDVSTVLSLLYKYQERFDIVQLFTEEEFKH WMLGHDENSDSNVVKSYVVEDENGIITDYFSYYLLPFTVL DNAQHDELGIAYLFYYASDSFEKPNYKKRLNELITDALIT SKKFGVDVFNCLTCQDNTYFLKDCKFGSGDGFLNYYLFNY RTFPMDGGIDKKTKEVVEDQTSGIGVVLL Description Functional site 1) chain A residue 451 type sequence L description C-TERM CARBOXYLATE POSTULATED AS SUBSTRATE BINDING, SINCE IT LIES ON FLOOR OF DEEP POCKET. source : AVE 2) chain B residue 451 type sequence L description C-TERM CARBOXYLATE POSTULATED AS SUBSTRATE BINDING, SINCE IT LIES ON FLOOR OF DEEP POCKET. source : BVE 3) chain C residue 451 type sequence L description C-TERM CARBOXYLATE POSTULATED AS SUBSTRATE BINDING, SINCE IT LIES ON FLOOR OF DEEP POCKET. source : CVE 4) chain B residue 107 type sequence Y description BINDING SITE FOR RESIDUE GOL B 1 source : AC1 5) chain B residue 119 type sequence Y description BINDING SITE FOR RESIDUE GOL B 1 source : AC1 6) chain B residue 175 type sequence N description BINDING SITE FOR RESIDUE GOL B 1 source : AC1 7) chain B residue 176 type sequence F description BINDING SITE FOR RESIDUE GOL B 1 source : AC1 8) chain B residue 451 type sequence L description BINDING SITE FOR RESIDUE GOL B 1 source : AC1 9) chain B residue 225 type sequence Y description BINDING SITE FOR RESIDUE GOL B 2 source : AC2 10) chain B residue 335 type sequence Y description BINDING SITE FOR RESIDUE GOL B 2 source : AC2 11) chain B residue 337 type sequence L description BINDING SITE FOR RESIDUE GOL B 2 source : AC2 12) chain B residue 354 type sequence Y description BINDING SITE FOR RESIDUE GOL B 2 source : AC2 13) chain B residue 451 type sequence L description BINDING SITE FOR RESIDUE GOL B 2 source : AC2 14) chain A residue 225 type sequence Y description BINDING SITE FOR RESIDUE GOL A 3 source : AC3 15) chain A residue 337 type sequence L description BINDING SITE FOR RESIDUE GOL A 3 source : AC3 16) chain A residue 451 type sequence L description BINDING SITE FOR RESIDUE GOL A 3 source : AC3 17) chain A residue 107 type sequence Y description BINDING SITE FOR RESIDUE GOL A 4 source : AC4 18) chain A residue 119 type sequence Y description BINDING SITE FOR RESIDUE GOL A 4 source : AC4 19) chain A residue 175 type sequence N description BINDING SITE FOR RESIDUE GOL A 4 source : AC4 20) chain A residue 176 type sequence F description BINDING SITE FOR RESIDUE GOL A 4 source : AC4 21) chain A residue 337 type sequence L description BINDING SITE FOR RESIDUE GOL A 4 source : AC4 22) chain C residue 107 type sequence Y description BINDING SITE FOR RESIDUE GOL C 5 source : AC5 23) chain C residue 119 type sequence Y description BINDING SITE FOR RESIDUE GOL C 5 source : AC5 24) chain C residue 175 type sequence N description BINDING SITE FOR RESIDUE GOL C 5 source : AC5 25) chain C residue 176 type sequence F description BINDING SITE FOR RESIDUE GOL C 5 source : AC5 26) chain C residue 337 type sequence L description BINDING SITE FOR RESIDUE GOL C 5 source : AC5 27) chain C residue 451 type sequence L description BINDING SITE FOR RESIDUE GOL C 5 source : AC5 28) chain C residue 225 type sequence Y description BINDING SITE FOR RESIDUE GOL C 6 source : AC6 29) chain C residue 335 type sequence Y description BINDING SITE FOR RESIDUE GOL C 6 source : AC6 30) chain C residue 337 type sequence L description BINDING SITE FOR RESIDUE GOL C 6 source : AC6 31) chain C residue 451 type sequence L description BINDING SITE FOR RESIDUE GOL C 6 source : AC6 32) chain A residue 161 type sequence K description BINDING SITE FOR RESIDUE GOL A 7 source : AC7 33) chain A residue 283 type sequence Y description BINDING SITE FOR RESIDUE GOL A 7 source : AC7 34) chain A residue 286 type sequence Q description BINDING SITE FOR RESIDUE GOL A 7 source : AC7 35) chain A residue 287 type sequence E description BINDING SITE FOR RESIDUE GOL A 7 source : AC7 36) chain A residue 294 type sequence L description BINDING SITE FOR RESIDUE GOL A 7 source : AC7 37) chain A residue 173 type sequence E description BINDING SITE FOR RESIDUE GOL A 8 source : AC8 38) chain A residue 293 type sequence Q description BINDING SITE FOR RESIDUE GOL A 8 source : AC8 39) chain A residue 303 type sequence W description BINDING SITE FOR RESIDUE GOL A 8 source : AC8 40) chain A residue 356 type sequence F description BINDING SITE FOR RESIDUE GOL A 8 source : AC8 41) chain A residue 357 type sequence Y description BINDING SITE FOR RESIDUE GOL A 8 source : AC8 42) chain A residue 449 type sequence V description BINDING SITE FOR RESIDUE GOL A 8 source : AC8 43) chain A residue 451 type sequence L description BINDING SITE FOR RESIDUE GOL A 8 source : AC8 44) chain A residue 107 type sequence Y description BINDING SITE FOR RESIDUE GOL A 9 source : AC9 45) chain A residue 211 type sequence T description BINDING SITE FOR RESIDUE GOL A 9 source : AC9 46) chain A residue 415 type sequence L description BINDING SITE FOR RESIDUE GOL A 9 source : AC9 47) chain A residue 451 type sequence L description BINDING SITE FOR RESIDUE GOL A 9 source : AC9 48) chain C residue 173 type sequence E description BINDING SITE FOR RESIDUE GOL C 10 source : BC1 49) chain C residue 293 type sequence Q description BINDING SITE FOR RESIDUE GOL C 10 source : BC1 50) chain C residue 303 type sequence W description BINDING SITE FOR RESIDUE GOL C 10 source : BC1 51) chain C residue 449 type sequence V description BINDING SITE FOR RESIDUE GOL C 10 source : BC1 52) chain C residue 451 type sequence L description BINDING SITE FOR RESIDUE GOL C 10 source : BC1 53) chain B residue 133 type sequence W description BINDING SITE FOR RESIDUE GOL B 11 source : BC2 54) chain B residue 135 type sequence K description BINDING SITE FOR RESIDUE GOL B 11 source : BC2 55) chain B residue 74 type sequence N description BINDING SITE FOR RESIDUE GOL B 12 source : BC3 56) chain B residue 76 type sequence P description BINDING SITE FOR RESIDUE GOL B 12 source : BC3 57) chain B residue 136 type sequence D description BINDING SITE FOR RESIDUE GOL B 12 source : BC3 58) chain B residue 198 type sequence R description BINDING SITE FOR RESIDUE GOL B 12 source : BC3 59) chain B residue 199 type sequence R description BINDING SITE FOR RESIDUE GOL B 12 source : BC3 60) chain A residue 74 type sequence N description BINDING SITE FOR RESIDUE GOL A 13 source : BC4 61) chain A residue 136 type sequence D description BINDING SITE FOR RESIDUE GOL A 13 source : BC4 62) chain A residue 198 type sequence R description BINDING SITE FOR RESIDUE GOL A 13 source : BC4 63) chain A residue 199 type sequence R description BINDING SITE FOR RESIDUE GOL A 13 source : BC4 64) chain C residue 74 type sequence N description BINDING SITE FOR RESIDUE GOL C 14 source : BC5 65) chain C residue 75 type sequence D description BINDING SITE FOR RESIDUE GOL C 14 source : BC5 66) chain C residue 136 type sequence D description BINDING SITE FOR RESIDUE GOL C 14 source : BC5 67) chain C residue 198 type sequence R description BINDING SITE FOR RESIDUE GOL C 14 source : BC5 68) chain A residue 217 type sequence P description BINDING SITE FOR RESIDUE GOL A 15 source : BC6 69) chain A residue 218 type sequence T description BINDING SITE FOR RESIDUE GOL A 15 source : BC6 70) chain A residue 418 type sequence Y description BINDING SITE FOR RESIDUE GOL A 15 source : BC6 71) chain A residue 420 type sequence F description BINDING SITE FOR RESIDUE GOL A 15 source : BC6 72) chain A residue 423 type sequence R description BINDING SITE FOR RESIDUE GOL A 15 source : BC6 73) chain B residue 166 type sequence N description BINDING SITE FOR RESIDUE GOL A 15 source : BC6 74) chain A residue 164 type sequence K description BINDING SITE FOR RESIDUE GOL A 16 source : BC7 75) chain A residue 287 type sequence E description BINDING SITE FOR RESIDUE GOL A 16 source : BC7 76) chain A residue 288 type sequence R description BINDING SITE FOR RESIDUE GOL A 16 source : BC7 77) chain A residue 289 type sequence F description BINDING SITE FOR RESIDUE GOL A 16 source : BC7 78) chain A residue 290 type sequence D description BINDING SITE FOR RESIDUE GOL A 16 source : BC7 79) chain B residue 173 type sequence E description BINDING SITE FOR RESIDUE GOL B 17 source : BC8 80) chain B residue 293 type sequence Q description BINDING SITE FOR RESIDUE GOL B 17 source : BC8 81) chain B residue 303 type sequence W description BINDING SITE FOR RESIDUE GOL B 17 source : BC8 82) chain B residue 356 type sequence F description BINDING SITE FOR RESIDUE GOL B 17 source : BC8 83) chain B residue 449 type sequence V description BINDING SITE FOR RESIDUE GOL B 17 source : BC8 84) chain B residue 451 type sequence L description BINDING SITE FOR RESIDUE GOL B 17 source : BC8 85) chain A residue 314 type sequence N description BINDING SITE FOR RESIDUE GOL A 18 source : BC9 86) chain A residue 317 type sequence K description BINDING SITE FOR RESIDUE GOL A 18 source : BC9 87) chain A residue 336 type sequence L description BINDING SITE FOR RESIDUE GOL A 18 source : BC9 88) chain A residue 386 type sequence F description BINDING SITE FOR RESIDUE GOL A 18 source : BC9 89) chain A residue 451 type ACT_SITE sequence L description Proton acceptor; via carboxylate => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 90) chain B residue 451 type ACT_SITE sequence L description Proton acceptor; via carboxylate => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 91) chain C residue 451 type ACT_SITE sequence L description Proton acceptor; via carboxylate => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 92) chain A residue 177 type BINDING sequence L description BINDING => ECO:0000269|PubMed:12401496, ECO:0007744|PDB:1IYK source Swiss-Prot : SWS_FT_FI2 93) chain A residue 185 type BINDING sequence N description BINDING => ECO:0000269|PubMed:12401496, ECO:0007744|PDB:1IYK source Swiss-Prot : SWS_FT_FI2 94) chain B residue 177 type BINDING sequence L description BINDING => ECO:0000269|PubMed:12401496, ECO:0007744|PDB:1IYK source Swiss-Prot : SWS_FT_FI2 95) chain B residue 185 type BINDING sequence N description BINDING => ECO:0000269|PubMed:12401496, ECO:0007744|PDB:1IYK source Swiss-Prot : SWS_FT_FI2 96) chain C residue 177 type BINDING sequence L description BINDING => ECO:0000269|PubMed:12401496, ECO:0007744|PDB:1IYK source Swiss-Prot : SWS_FT_FI2 97) chain C residue 185 type BINDING sequence N description BINDING => ECO:0000269|PubMed:12401496, ECO:0007744|PDB:1IYK source Swiss-Prot : SWS_FT_FI2 98) chain A residue 173-181 type prosite sequence EINFLCIHK description NMT_1 Myristoyl-CoA:protein N-myristoyltransferase signature 1. EINFLCiHK source prosite : PS00975 99) chain A residue 407-413 type prosite sequence KFGSGDG description NMT_2 Myristoyl-CoA:protein N-myristoyltransferase signature 2. KFGsGDG source prosite : PS00976

Display surface Download Links