eF-site ID 1nkh-ABCD PDB Code 1nkh Chain A, B, C, D click to enlarge Title Crystal structure of Lactose synthase complex with UDP and Manganese Classification TRANSFERASE ACTIVATOR/TRANSFERASE Compound ALPHA-LACTALBUMIN Source Mus musculus (Mouse) (B4GT1_BOVIN) Sequence A:  TELTKCKVSHAIKDIDGYQGISLLEWACVLFHTSGYDTQA VVNDNGSTEYGLFQISDRFWCKSSEFPESENICGISCDKL LDDELDDDIACAKKILAIKGIDYWKAYKPMCSEKLEQWRC EKP B:  LTACPEESPLLVGPMLIEFNIPVDLKLVEQQNPKVKLGGR YTPMDCISPHKVAIIIPFRNRQEHLKYWLYYLHPILQRQQ LDYGIYVINQAGESMFNRAKLLNVGFKEALKDYDYNCFVF SDVDLIPMNDHNTYRCFSQPRHISVAMDKFGFSLPYVQYF GGVSALSKQQFLSINGFPNNYWGWGGEDDDIYNRLAFRGM SVSRPNAVIGKCRMIRHSRDKKNEPNPQRFDRIAHTKETM LSDGLNSLTYMVLEVQRYPLYTKITVDIGTPS C:  TELTKCKVSHAIKDIDGYQGISLLEWACVLFHTSGYDTQA VVNDNGSTEYGLFQISDRFWCKSSEFPESENICGISCDKL LDDELDDDIACAKKILAIKGIDYWKAYKPMCSEKLEQWRC EKP D:  LTACPEESPLLVGPMLIEFNIPVDLKLVEQQNPKVKLGGR YTPMDCISPHKVAIIIPFRNRQEHLKYWLYYLHPILQRQQ LDYGIYVINQAGESMFNRAKLLNVGFKEALKDYDYNCFVF SDVDLIPMNDHNTYRCFSQPRHISVAMDKFGFSLPYVQYF GGVSALSKQQFLSINGFPNNYWGWGGEDDDIYNRLAFRGM SVSRPNAVIGKCRMIRHSRDKKNEPNPQRFDRIAHTKETM LSDGLNSLTYMVLEVQRYPLYTKITVDIGTPS Description (1)  ALPHA-LACTALBUMIN/BETA-1,4-GALACTOSYLTRANSFERASE (E.C.2.4.1.22, E.C.2.4.1.90, E.C.2.4.1.38) COMPLEX Functional site 1) chain A residue 79 type sequence K description BINDING SITE FOR RESIDUE CA A 805 source : AC1 2) chain A residue 82 type sequence D description BINDING SITE FOR RESIDUE CA A 805 source : AC1 3) chain A residue 84 type sequence E description BINDING SITE FOR RESIDUE CA A 805 source : AC1 4) chain A residue 87 type sequence D description BINDING SITE FOR RESIDUE CA A 805 source : AC1 5) chain A residue 88 type sequence D description BINDING SITE FOR RESIDUE CA A 805 source : AC1 6) chain C residue 79 type sequence K description BINDING SITE FOR RESIDUE CA C 806 source : AC2 7) chain C residue 82 type sequence D description BINDING SITE FOR RESIDUE CA C 806 source : AC2 8) chain C residue 84 type sequence E description BINDING SITE FOR RESIDUE CA C 806 source : AC2 9) chain C residue 87 type sequence D description BINDING SITE FOR RESIDUE CA C 806 source : AC2 10) chain C residue 88 type sequence D description BINDING SITE FOR RESIDUE CA C 806 source : AC2 11) chain B residue 254 type sequence D description BINDING SITE FOR RESIDUE MN B 807 source : AC3 12) chain B residue 344 type sequence M description BINDING SITE FOR RESIDUE MN B 807 source : AC3 13) chain B residue 347 type sequence H description BINDING SITE FOR RESIDUE MN B 807 source : AC3 14) chain D residue 254 type sequence D description BINDING SITE FOR RESIDUE MN D 808 source : AC4 15) chain D residue 344 type sequence M description BINDING SITE FOR RESIDUE MN D 808 source : AC4 16) chain D residue 347 type sequence H description BINDING SITE FOR RESIDUE MN D 808 source : AC4 17) chain D residue 148 type sequence E description BINDING SITE FOR RESIDUE SO4 D 818 source : AC5 18) chain D residue 149 type sequence F description BINDING SITE FOR RESIDUE SO4 D 818 source : AC5 19) chain D residue 150 type sequence N description BINDING SITE FOR RESIDUE SO4 D 818 source : AC5 20) chain D residue 343 type sequence R description BINDING SITE FOR RESIDUE SO4 D 818 source : AC5 21) chain A residue 4 type sequence T description BINDING SITE FOR RESIDUE SO4 A 819 source : AC6 22) chain A residue 7 type sequence K description BINDING SITE FOR RESIDUE SO4 A 819 source : AC6 23) chain B residue 187 type sequence P description BINDING SITE FOR RESIDUE UDP B 809 source : AC7 24) chain B residue 188 type sequence F description BINDING SITE FOR RESIDUE UDP B 809 source : AC7 25) chain B residue 189 type sequence R description BINDING SITE FOR RESIDUE UDP B 809 source : AC7 26) chain B residue 191 type sequence R description BINDING SITE FOR RESIDUE UDP B 809 source : AC7 27) chain B residue 226 type sequence F description BINDING SITE FOR RESIDUE UDP B 809 source : AC7 28) chain B residue 252 type sequence D description BINDING SITE FOR RESIDUE UDP B 809 source : AC7 29) chain B residue 253 type sequence V description BINDING SITE FOR RESIDUE UDP B 809 source : AC7 30) chain B residue 254 type sequence D description BINDING SITE FOR RESIDUE UDP B 809 source : AC7 31) chain B residue 314 type sequence W description BINDING SITE FOR RESIDUE UDP B 809 source : AC7 32) chain B residue 344 type sequence M description BINDING SITE FOR RESIDUE UDP B 809 source : AC7 33) chain B residue 347 type sequence H description BINDING SITE FOR RESIDUE UDP B 809 source : AC7 34) chain B residue 350 type sequence D description BINDING SITE FOR RESIDUE UDP B 809 source : AC7 35) chain D residue 187 type sequence P description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 36) chain D residue 188 type sequence F description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 37) chain D residue 189 type sequence R description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 38) chain D residue 191 type sequence R description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 39) chain D residue 226 type sequence F description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 40) chain D residue 252 type sequence D description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 41) chain D residue 253 type sequence V description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 42) chain D residue 254 type sequence D description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 43) chain D residue 314 type sequence W description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 44) chain D residue 344 type sequence M description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 45) chain D residue 347 type sequence H description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 46) chain D residue 349 type sequence R description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 47) chain D residue 350 type sequence D description BINDING SITE FOR RESIDUE UDP D 810 source : AC8 48) chain B residue 155 type sequence L description BINDING SITE FOR RESIDUE UDP B 811 source : AC9 49) chain B residue 156 type sequence K description BINDING SITE FOR RESIDUE UDP B 811 source : AC9 50) chain B residue 159 type sequence E description BINDING SITE FOR RESIDUE UDP B 811 source : AC9 51) chain B residue 192 type sequence Q description BINDING SITE FOR RESIDUE UDP B 811 source : AC9 52) chain B residue 386 type sequence Q description BINDING SITE FOR RESIDUE UDP B 811 source : AC9 53) chain B residue 388 type sequence Y description BINDING SITE FOR RESIDUE UDP B 811 source : AC9 54) chain B residue 389 type sequence P description BINDING SITE FOR RESIDUE UDP B 811 source : AC9 55) chain B residue 390 type sequence L description BINDING SITE FOR RESIDUE UDP B 811 source : AC9 56) chain B residue 391 type sequence Y description BINDING SITE FOR RESIDUE UDP B 811 source : AC9 57) chain B residue 393 type sequence K description BINDING SITE FOR RESIDUE UDP B 811 source : AC9 58) chain D residue 155 type sequence L description BINDING SITE FOR RESIDUE UDP D 812 source : BC1 59) chain D residue 156 type sequence K description BINDING SITE FOR RESIDUE UDP D 812 source : BC1 60) chain D residue 159 type sequence E description BINDING SITE FOR RESIDUE UDP D 812 source : BC1 61) chain D residue 386 type sequence Q description BINDING SITE FOR RESIDUE UDP D 812 source : BC1 62) chain D residue 388 type sequence Y description BINDING SITE FOR RESIDUE UDP D 812 source : BC1 63) chain D residue 389 type sequence P description BINDING SITE FOR RESIDUE UDP D 812 source : BC1 64) chain D residue 390 type sequence L description BINDING SITE FOR RESIDUE UDP D 812 source : BC1 65) chain D residue 391 type sequence Y description BINDING SITE FOR RESIDUE UDP D 812 source : BC1 66) chain A residue 2 type sequence E description BINDING SITE FOR RESIDUE PG4 A 813 source : BC2 67) chain A residue 31 type sequence F description BINDING SITE FOR RESIDUE PG4 A 813 source : BC2 68) chain A residue 32 type sequence H description BINDING SITE FOR RESIDUE PG4 A 813 source : BC2 69) chain A residue 34 type sequence S description BINDING SITE FOR RESIDUE PG4 A 813 source : BC2 70) chain A residue 35 type sequence G description BINDING SITE FOR RESIDUE PG4 A 813 source : BC2 71) chain A residue 40 type sequence A description BINDING SITE FOR RESIDUE PG4 A 813 source : BC2 72) chain B residue 279 type sequence K description BINDING SITE FOR RESIDUE PG4 A 813 source : BC2 73) chain B residue 314 type sequence W description BINDING SITE FOR RESIDUE PG4 A 813 source : BC2 74) chain B residue 349 type sequence R description BINDING SITE FOR RESIDUE PG4 A 813 source : BC2 75) chain C residue 31 type sequence F description BINDING SITE FOR RESIDUE PG4 C 814 source : BC3 76) chain C residue 32 type sequence H description BINDING SITE FOR RESIDUE PG4 C 814 source : BC3 77) chain C residue 33 type sequence T description BINDING SITE FOR RESIDUE PG4 C 814 source : BC3 78) chain C residue 34 type sequence S description BINDING SITE FOR RESIDUE PG4 C 814 source : BC3 79) chain C residue 35 type sequence G description BINDING SITE FOR RESIDUE PG4 C 814 source : BC3 80) chain C residue 37 type sequence D description BINDING SITE FOR RESIDUE PG4 C 814 source : BC3 81) chain C residue 40 type sequence A description BINDING SITE FOR RESIDUE PG4 C 814 source : BC3 82) chain D residue 314 type sequence W description BINDING SITE FOR RESIDUE PG4 C 814 source : BC3 83) chain D residue 359 type sequence R description BINDING SITE FOR RESIDUE PG4 C 814 source : BC3 84) chain B residue 242 type sequence D description BINDING SITE FOR RESIDUE PG4 B 815 source : BC4 85) chain B residue 385 type sequence V description BINDING SITE FOR RESIDUE PG4 B 815 source : BC4 86) chain B residue 387 type sequence R description BINDING SITE FOR RESIDUE PG4 B 815 source : BC4 87) chain D residue 387 type sequence R description BINDING SITE FOR RESIDUE PG4 B 815 source : BC4 88) chain C residue 31 type sequence F description BINDING SITE FOR RESIDUE PG4 D 816 source : BC5 89) chain D residue 279 type sequence K description BINDING SITE FOR RESIDUE PG4 D 816 source : BC5 90) chain D residue 280 type sequence F description BINDING SITE FOR RESIDUE PG4 D 816 source : BC5 91) chain D residue 286 type sequence Y description BINDING SITE FOR RESIDUE PG4 D 816 source : BC5 92) chain D residue 289 type sequence Y description BINDING SITE FOR RESIDUE PG4 D 816 source : BC5 93) chain D residue 292 type sequence G description BINDING SITE FOR RESIDUE PG4 D 816 source : BC5 94) chain D residue 314 type sequence W description BINDING SITE FOR RESIDUE PG4 D 816 source : BC5 95) chain D residue 318 type sequence D description BINDING SITE FOR RESIDUE PG4 D 816 source : BC5 96) chain A residue 31 type sequence F description BINDING SITE FOR RESIDUE PG4 B 817 source : BC6 97) chain B residue 279 type sequence K description BINDING SITE FOR RESIDUE PG4 B 817 source : BC6 98) chain B residue 280 type sequence F description BINDING SITE FOR RESIDUE PG4 B 817 source : BC6 99) chain B residue 286 type sequence Y description BINDING SITE FOR RESIDUE PG4 B 817 source : BC6 100) chain B residue 314 type sequence W description BINDING SITE FOR RESIDUE PG4 B 817 source : BC6 101) chain B residue 316 type sequence G description BINDING SITE FOR RESIDUE PG4 B 817 source : BC6 102) chain B residue 318 type sequence D description BINDING SITE FOR RESIDUE PG4 B 817 source : BC6 103) chain B residue 319 type sequence D description BINDING SITE FOR RESIDUE PG4 B 817 source : BC6 104) chain B residue 252 type catalytic sequence D description 570 source MCSA : MCSA1 105) chain B residue 254 type catalytic sequence D description 570 source MCSA : MCSA1 106) chain B residue 314 type catalytic sequence W description 570 source MCSA : MCSA1 107) chain B residue 317 type catalytic sequence E description 570 source MCSA : MCSA1 108) chain B residue 318 type catalytic sequence D description 570 source MCSA : MCSA1 109) chain B residue 344 type catalytic sequence M description 570 source MCSA : MCSA1 110) chain B residue 347 type catalytic sequence H description 570 source MCSA : MCSA1 111) chain B residue 349 type catalytic sequence R description 570 source MCSA : MCSA1 112) chain D residue 252 type catalytic sequence D description 570 source MCSA : MCSA2 113) chain D residue 254 type catalytic sequence D description 570 source MCSA : MCSA2 114) chain D residue 314 type catalytic sequence W description 570 source MCSA : MCSA2 115) chain D residue 317 type catalytic sequence E description 570 source MCSA : MCSA2 116) chain D residue 318 type catalytic sequence D description 570 source MCSA : MCSA2 117) chain D residue 344 type catalytic sequence M description 570 source MCSA : MCSA2 118) chain D residue 347 type catalytic sequence H description 570 source MCSA : MCSA2 119) chain D residue 349 type catalytic sequence R description 570 source MCSA : MCSA2 120) chain A residue 73-91 type prosite sequence CGISCDKLLDDELDDDIAC description GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CgisCdkLlddELdddiaC source prosite : PS00128 121) chain B residue 187 type BINDING sequence P description source Swiss-Prot : SWS_FT_FI1 122) chain D residue 226 type BINDING sequence F description source Swiss-Prot : SWS_FT_FI1 123) chain D residue 253 type BINDING sequence V description source Swiss-Prot : SWS_FT_FI1 124) chain D residue 254 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 125) chain D residue 314 type BINDING sequence W description source Swiss-Prot : SWS_FT_FI1 126) chain D residue 316 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI1 127) chain D residue 347 type BINDING sequence H description source Swiss-Prot : SWS_FT_FI1 128) chain D residue 359 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI1 129) chain B residue 226 type BINDING sequence F description source Swiss-Prot : SWS_FT_FI1 130) chain B residue 253 type BINDING sequence V description source Swiss-Prot : SWS_FT_FI1 131) chain B residue 254 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 132) chain B residue 314 type BINDING sequence W description source Swiss-Prot : SWS_FT_FI1 133) chain B residue 316 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI1 134) chain B residue 347 type BINDING sequence H description source Swiss-Prot : SWS_FT_FI1 135) chain B residue 359 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI1 136) chain D residue 187 type BINDING sequence P description source Swiss-Prot : SWS_FT_FI1 137) chain A residue 45 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 138) chain C residue 45 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links