|
|
eF-site ID
|
1nj4-A |
|
PDB Code
|
1nj4 |
|
Chain
|
A |
|
click to enlarge
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Title
|
Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 1.9 A resolution |
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Classification
|
HYDROLASE |
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Compound
|
Penicillin-binding protein 5 |
|
Source
|
Escherichia coli (strain K12) (DACA_ECOLI) |
|
|
Sequence
|
A: |
LNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDP
ASLTKMMTSYVIGQAMKAGKFKETDLVTIGNKGSSLMFLK
PGMQVPVSQLIRDINLQSGNDACVAMADFAAGSQDAFVGL
MNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQAL
IRDVPNEYSIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGI
KTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGREAES
KKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGV
DKDVYLTIPRGRMKDLKASYVLNSSELHAPLQKNQVVGTI
NFQLDGKTIEQRPLVVLQEIPEG
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
44 |
| type |
ACT_SITE |
| sequence |
S
|
| description |
Acyl-ester intermediate
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
47 |
| type |
ACT_SITE |
| sequence |
K
|
| description |
Proton acceptor
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
A |
| residue |
110 |
| type |
ACT_SITE |
| sequence |
S
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
A |
| residue |
213 |
| type |
BINDING |
| sequence |
K
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|