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eF-site ID
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1nik-A |
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PDB Code
|
1nik |
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Chain
|
A |
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click to enlarge
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Title
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Wild Type RNA Polymerase II |
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Classification
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TRANSCRIPTION |
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Compound
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RPB1 |
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Source
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ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
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A: |
VGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETM
DETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHF
GHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNEL
MRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSLVSRGGC
GNTQPTIRKDGLKLVGSWKLRVLSTEEILNIFKHISVKDF
TSLGFNEVFSRPEWMILTCLPVPPPPVRPSEDDLTFKLAD
ILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDI
AGQPQAPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVIS
GDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRN
GPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVER
HIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSV
TSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSP
QSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVP
DWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEG
TTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVT
REKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGP
TMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESF
EDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGS
FINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSP
ESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAET
GYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMD
AAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLE
SGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANW
PLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQ
ENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQE
YRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGE
PATQMTLKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGH
AADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIP
EDEEIIQLHFSLQQSPWLLRLELDRAAMNDKDLTMGQVGE
RIKQTFKNDLFVIWSEDNDEKLIIRCRVVAEEDHMLKKIE
NTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEW
VLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAG
RAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSV
TRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGV
SENVILGQMAPIGTGAFDVMIDEESLVK
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Description
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Functional site
|
|
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1)
|
chain |
A |
| residue |
110 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN A 1734
|
| source |
: AC1
|
|
|
2)
|
chain |
A |
| residue |
167 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN A 1734
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
67 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN A 1735
|
| source |
: AC2
|
|
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4)
|
chain |
A |
| residue |
70 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN A 1735
|
| source |
: AC2
|
|
|
5)
|
chain |
A |
| residue |
77 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN A 1735
|
| source |
: AC2
|
|
|
6)
|
chain |
A |
| residue |
80 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN A 1735
|
| source |
: AC2
|
|
|
7)
|
chain |
A |
| residue |
483 |
| type |
catalytic |
| sequence |
D
|
| description |
788
|
| source |
MCSA : MCSA1
|
|
|
8)
|
chain |
A |
| residue |
485 |
| type |
catalytic |
| sequence |
D
|
| description |
788
|
| source |
MCSA : MCSA1
|
|
|
9)
|
chain |
A |
| residue |
483 |
| type |
ZN_FING |
| sequence |
D
|
| description |
C4-type
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
A |
| residue |
485 |
| type |
ZN_FING |
| sequence |
D
|
| description |
C4-type
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
11)
|
chain |
A |
| residue |
107 |
| type |
ZN_FING |
| sequence |
C
|
| description |
C4-type
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
12)
|
chain |
A |
| residue |
110 |
| type |
ZN_FING |
| sequence |
C
|
| description |
C4-type
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
13)
|
chain |
A |
| residue |
148 |
| type |
ZN_FING |
| sequence |
C
|
| description |
C4-type
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
14)
|
chain |
A |
| residue |
167 |
| type |
ZN_FING |
| sequence |
C
|
| description |
C4-type
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
15)
|
chain |
A |
| residue |
481 |
| type |
ZN_FING |
| sequence |
D
|
| description |
C4-type
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|