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eF-site ID
|
1ni2-A |
|
PDB Code
|
1ni2 |
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Chain
|
A |
|
click to enlarge
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Title
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Structure of the active FERM domain of Ezrin |
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Classification
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STRUCTURAL PROTEIN |
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Compound
|
Ezrin |
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Source
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Homo sapiens (Human) (EZRI_HUMAN) |
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Sequence
|
A: |
PKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLRE
VWYFGLHYVDNKGFPTWLKLDKKVSAQEVRKENPLQFKFR
AKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET
AVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQH
KLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMY
GINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFP
WSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRIL
QLCMGNHELYMRRRKP
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
58-88 |
| type |
prosite |
| sequence |
WLKLDKKVSAQEVRKENPLQFKFRAKFYPED
|
| description |
FERM_1 FERM domain signature 1. WLkldKkVsaQe.Vrkenplq.FkfrakFYpeD
|
| source |
prosite : PS00660
|
|
|
2)
|
chain |
A |
| residue |
176-205 |
| type |
prosite |
| sequence |
HAEHRGMLKDNAMLEYLKIAQDLEMYGINY
|
| description |
FERM_2 FERM domain signature 2. HaehrgmlkdNAmleYLki.AqdLemYGiNY
|
| source |
prosite : PS00661
|
|
|
3)
|
chain |
A |
| residue |
61 |
| type |
MOD_RES |
| sequence |
L
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
147 |
| type |
MOD_RES |
| sequence |
L
|
| description |
Phosphotyrosine; by PDGFR => ECO:0000269|PubMed:1382070, ECO:0000269|PubMed:18046454
|
| source |
Swiss-Prot : SWS_FT_FI2
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