eF-site ID 1ngg-A
PDB Code 1ngg
Chain A

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Title STRUCTURAL BASIS OF THE 70-KILODALTON HEAT SHOCK COGNATE PROTEIN ATP HYDROLYTIC ACTIVITY, II. STRUCTURE OF THE ACTIVE SITE WITH ADP OR ATP BOUND TO WILD TYPE AND MUTANT ATPASE FRAGMENT
Classification HYDROLASE(ACTING ON ACID ANHYDRIDES)
Compound HEAT-SHOCK COGNATE 70 kD PROTEIN
Source Bos taurus (Bovine) (HSP7C_BOVIN)
Sequence A:  KGPAVGISLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYV
AFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAV
VQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSM
VLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAG
TIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGG
GTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFI
AEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASI
EIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALR
DAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKS
INPDEAVAYGAAVQAAILS
Description


Functional site

1) chain A
residue 12
type
sequence G
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

2) chain A
residue 13
type
sequence T
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

3) chain A
residue 14
type
sequence T
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

4) chain A
residue 15
type
sequence Y
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

5) chain A
residue 201
type
sequence G
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

6) chain A
residue 202
type
sequence G
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

7) chain A
residue 203
type
sequence G
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

8) chain A
residue 204
type
sequence T
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

9) chain A
residue 230
type
sequence G
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

10) chain A
residue 268
type
sequence E
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

11) chain A
residue 271
type
sequence K
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

12) chain A
residue 272
type
sequence R
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

13) chain A
residue 275
type
sequence S
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

14) chain A
residue 338
type
sequence G
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

15) chain A
residue 339
type
sequence G
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

16) chain A
residue 340
type
sequence S
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

17) chain A
residue 342
type
sequence R
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

18) chain A
residue 343
type
sequence I
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

19) chain A
residue 366
type
sequence D
description BINDING SITE FOR RESIDUE ATP A 486
source : AC2

20) chain A
residue 10
type catalytic
sequence S
description 656
source MCSA : MCSA1

21) chain A
residue 71
type catalytic
sequence K
description 656
source MCSA : MCSA1

22) chain A
residue 175
type catalytic
sequence E
description 656
source MCSA : MCSA1

23) chain A
residue 199
type catalytic
sequence D
description 656
source MCSA : MCSA1

24) chain A
residue 153
type MOD_RES
sequence S
description Phosphoserine => ECO:0000250|UniProtKB:P11142
source Swiss-Prot : SWS_FT_FI4

25) chain A
residue 329
type MOD_RES
sequence S
description Phosphoserine => ECO:0000250|UniProtKB:P11142
source Swiss-Prot : SWS_FT_FI4

26) chain A
residue 362
type MOD_RES
sequence S
description Phosphoserine => ECO:0000250|UniProtKB:P11142
source Swiss-Prot : SWS_FT_FI4

27) chain A
residue 246
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000250|UniProtKB:P11142
source Swiss-Prot : SWS_FT_FI5

28) chain A
residue 319
type MOD_RES
sequence K
description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P63017
source Swiss-Prot : SWS_FT_FI6

29) chain A
residue 108
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000250|UniProtKB:P63017
source Swiss-Prot : SWS_FT_FI3

30) chain A
residue 328
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000250|UniProtKB:P63017
source Swiss-Prot : SWS_FT_FI3

31) chain A
residue 197-210
type prosite
sequence IFDLGGGTFDVSIL
description HSP70_2 Heat shock hsp70 proteins family signature 2. IFDLGGGTfdvSIL
source prosite : PS00329

32) chain A
residue 334-348
type prosite
sequence IVLVGGSTRIPKIQK
description HSP70_3 Heat shock hsp70 proteins family signature 3. IvLvGGsTRIPkIqK
source prosite : PS01036

33) chain A
residue 12
type BINDING
sequence G
description
source Swiss-Prot : SWS_FT_FI1

34) chain A
residue 71
type BINDING
sequence K
description
source Swiss-Prot : SWS_FT_FI1

35) chain A
residue 202
type BINDING
sequence G
description
source Swiss-Prot : SWS_FT_FI1

36) chain A
residue 268
type BINDING
sequence E
description
source Swiss-Prot : SWS_FT_FI1

37) chain A
residue 339
type BINDING
sequence G
description
source Swiss-Prot : SWS_FT_FI1


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