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|
eF-site ID
|
1nez-ABGH |
|
PDB Code
|
1nez |
|
Chain
|
A, B, G, H |
|
click to enlarge
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Title
|
The Crystal Structure of a TL/CD8aa Complex at 2.1A resolution:Implications for Memory T cell Generation, Co-receptor Preference and Affinity |
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Classification
|
IMMUNE SYSTEM |
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Compound
|
H-2 class I histocompatibility antigen, TLA(C) alpha chain |
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Source
|
(CD8A_MOUSE) |
|
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Sequence
|
A: |
GSHSLRYFYTALSRPAISEPWYIAVGYLDDTQFARFDSAG
ETGTYKLSAPWVEQEGPEYWARETEIVTSNAQFFRENLQT
MLDYYNLSQNGSHTIQVMYGCEVEFFGSLFRAYEQHGYDG
QDYIALNEDLKTWTAADMAAEITRSKWEQAGYTELRRTYL
EGPCKDSLLRYLENRKKTQECTDPPKTHVTHHARPEGDVT
LRCWALGFYPAHITLTWQLNGEELIQDTELVETRPAGDGT
FQKWAAVVVPSGEEQKYTCHVYHEGLPEPLTLRW
|
| B: |
IQKTPQIQVYSRHPPENGKPNILNCYVTQFHPPHIEIQML
KNGKKIPKVEMSDMSFSKDWSFYILAHTEFTPTETDTYAC
RVKHDSMAEPKTVYWDRDM
|
| G: |
APELRIFPKKMDAELGQKVDLVCEVLGSVSQGCSWLFQNS
SSKLPQPTFVVYMASSHNKITWDEKLNSSKLFSAMRDTNN
KYVLTLNKFSKENEGYYFCSVISNSVMYFSSVVPVLQKVS
SA
|
| H: |
KPQAPELRIFPKKMDAELGQKVDLVCEVLGSVSQGCSWLF
QNSSSKLPQPTFVVYMASSHNKITWDEKLNSSKLFSAMRD
TNNKYVLTLNKFSKENEGYYFCSVISNSVMYFSSVVPVLQ
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Description
|
(1) |
H-2 class I histocompatibility antigen, TLA(C) alpha chain/Beta-2-microglobulin/T-cell surface glycoprotein CD8 alpha chain
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
78-84 |
| type |
prosite |
| sequence |
YACRVKH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCHVYH
|
| source |
prosite : PS00290
|
|
|
2)
|
chain |
A |
| residue |
257-263 |
| type |
prosite |
| sequence |
YTCHVYH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCHVYH
|
| source |
prosite : PS00290
|
|
|
3)
|
chain |
G |
| residue |
70 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
H |
| residue |
70 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
H |
| residue |
42 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18929574
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
90 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18929574
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
G |
| residue |
42 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18929574
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|