eF-site ID 1ndm-ABC PDB Code 1ndm Chain A, B, C click to enlarge Title Crystal structure of Fab fragment of antibody HyHEL-26 complexed with lysozyme Classification IMMUNE SYSTEM/HYDROLASE Compound antibody kappa light chain Source Mus musculus (Mouse) (LYSC_CHICK) Sequence A:  DIVLTQSPATLSVTPGDSVSLSCRASQSISNNLHWYQQKS HESPRLLIKYASQSISGIPSRFSGSGSGTDFTLSINSVET EDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIFPP SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT STSPIVKSFNRNEC B:  EVQLQESGPSLVKPSQTLSLTCSVTGDSITSDYWSWIRKF PGNKLEYMGYISYSGSTYYHPSLKSRISITRDTSKNQYYL QLNSVTTEDTATYYCARWEMDYWGQGTSVTVSSAKTTAPS VYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLS SGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHP ASSTKVDKKI C:  KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNT QATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPC SALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDV QAWIRGCRL Description (1)  antibody kappa light chain/immunoglobulin gamma 1 chain/Lysozyme C (E.C.3.2.1.17) complex Functional site 1) chain C residue 635 type catalytic sequence E description 203 source MCSA : MCSA1 2) chain C residue 646 type catalytic sequence N description 203 source MCSA : MCSA1 3) chain C residue 648 type catalytic sequence D description 203 source MCSA : MCSA1 4) chain C residue 650 type catalytic sequence S description 203 source MCSA : MCSA1 5) chain C residue 652 type catalytic sequence D description 203 source MCSA : MCSA1 6) chain C residue 659 type catalytic sequence N description 203 source MCSA : MCSA1 7) chain C residue 701 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI2 8) chain C residue 635 type ACT_SITE sequence E description source Swiss-Prot : SWS_FT_FI1 9) chain C residue 652 type ACT_SITE sequence D description source Swiss-Prot : SWS_FT_FI1 10) chain C residue 676-694 type prosite sequence CNIPCSALLSSDITASVNC description GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC source prosite : PS00128 11) chain A residue 192-198 type prosite sequence YTCEATH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH source prosite : PS00290

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