|
|
eF-site ID
|
1nby-ABC |
|
PDB Code
|
1nby |
|
Chain
|
A, B, C |
|
click to enlarge
|
|
|
Title
|
Crystal Structure of HyHEL-63 complexed with HEL mutant K96A |
|
Classification
|
IMMUNE SYSTEM/HYDROLASE |
|
Compound
|
antibody kappa light chain |
|
Source
|
null (LYSC_CHICK) |
|
|
Sequence
|
A: |
DIVLTQSPATLSVTPGDSVSLSCRASQSISNNLHWYQQKS
HESPRLLIKYASQSISGIPSRFSGSGSGTDFTLSINSVET
EDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIFPP
SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL
NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT
STSPIVKSFNRNEC
|
| B: |
EVQLQESGPSLVKPSQTLSLTCSVTGDSVTSDYWSWIRKF
PGNKLEYMGYISYSGSTYYHPSLKSRISITRDTSKNQYYL
QLNSVTTEDTATYYCASWGGDVWGAGTTVTVSSAKTTAPS
VYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLS
SGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHP
ASSTKVDKKI
|
| C: |
KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNT
QATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPC
SALLSSDITASVNCAAKIVSDGNGMNAWVAWRNRCKGTDV
QAWIRGCRL
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
635 |
| type |
catalytic |
| sequence |
E
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
2)
|
chain |
C |
| residue |
646 |
| type |
catalytic |
| sequence |
N
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
3)
|
chain |
C |
| residue |
648 |
| type |
catalytic |
| sequence |
D
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
4)
|
chain |
C |
| residue |
650 |
| type |
catalytic |
| sequence |
S
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
5)
|
chain |
C |
| residue |
652 |
| type |
catalytic |
| sequence |
D
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
6)
|
chain |
C |
| residue |
659 |
| type |
catalytic |
| sequence |
N
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
7)
|
chain |
C |
| residue |
676-694 |
| type |
prosite |
| sequence |
CNIPCSALLSSDITASVNC
|
| description |
GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC
|
| source |
prosite : PS00128
|
|
|
8)
|
chain |
A |
| residue |
192-198 |
| type |
prosite |
| sequence |
YTCEATH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
|
| source |
prosite : PS00290
|
|
|
9)
|
chain |
C |
| residue |
652 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
C |
| residue |
635 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
11)
|
chain |
C |
| residue |
701 |
| type |
BINDING |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|