|
|
eF-site ID
|
1nbf-A |
|
PDB Code
|
1nbf |
|
Chain
|
A |
|
click to enlarge
|
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Title
|
Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde |
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Classification
|
HYDROLASE |
|
Compound
|
Ubiquitin carboxyl-terminal hydrolase 7 |
|
Source
|
(UBIQ_HUMAN) |
|
|
Sequence
|
A: |
KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPT
EGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWET
LDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGK
MVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDY
VAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLM
RFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN
YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSR
CTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEV
LQAVTDHDIPQQLVERLQEEKRIEAQK
|
|
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Description
|
(1) |
Ubiquitin carboxyl-terminal hydrolase 7
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
218 |
| type |
catalytic |
| sequence |
N
|
| description |
789
|
| source |
MCSA : MCSA1
|
|
|
2)
|
chain |
A |
| residue |
223 |
| type |
catalytic |
| sequence |
C
|
| description |
789
|
| source |
MCSA : MCSA1
|
|
|
3)
|
chain |
A |
| residue |
464 |
| type |
catalytic |
| sequence |
H
|
| description |
789
|
| source |
MCSA : MCSA1
|
|
|
4)
|
chain |
A |
| residue |
481 |
| type |
catalytic |
| sequence |
D
|
| description |
789
|
| source |
MCSA : MCSA1
|
|
|
5)
|
chain |
A |
| residue |
215-230 |
| type |
prosite |
| sequence |
GLKNQGATCYMNSLLQ
|
| description |
USP_1 Ubiquitin specific protease (USP) domain signature 1. GLknqGAtCYMNSlLQ
|
| source |
prosite : PS00972
|
|
|
6)
|
chain |
A |
| residue |
448-465 |
| type |
prosite |
| sequence |
YILHAVLVHSGDNHGGHY
|
| description |
USP_2 Ubiquitin specific protease (USP) domain signature 2. YiLhAVlvHsGdnhg..GHY
|
| source |
prosite : PS00973
|
|
|
|