eF-site ID 1n54-AB PDB Code 1n54 Chain A, B click to enlarge Title Cap Binding Complex m7GpppG free Classification RNA BINDING PROTEIN Compound 80 kDa nuclear cap binding protein Source Homo sapiens (Human) (NCBP2_HUMAN) Sequence A:  ANETEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPN YKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGE FVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAP SMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKE LYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPH PQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEA LQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVM PGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKN KIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQ PGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSN FQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQ RILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALC LAVAFKSKATNDEIFSILKDVPNFNPLKIEVFVQTLLHLA AKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWR NHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRL FVWEILHSTIRKMNKHVLKIQKELEEAKEKLEEQIERLQE KVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLT PWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPH ILAVFQQFCALQA B:  LKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVG NLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCF VEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQY G Description Functional site 1) chain A residue 458 type sequence R description BINDING SITE FOR RESIDUE GOL B 1555 source : AC1 2) chain A residue 639 type sequence E description BINDING SITE FOR RESIDUE GOL B 1555 source : AC1 3) chain B residue 57 type sequence Y description BINDING SITE FOR RESIDUE GOL B 1555 source : AC1 4) chain B residue 58 type sequence E description BINDING SITE FOR RESIDUE GOL B 1555 source : AC1 5) chain B residue 61 type sequence S description BINDING SITE FOR RESIDUE GOL B 1555 source : AC1 6) chain A residue 607 type sequence K description BINDING SITE FOR RESIDUE GOL A 1556 source : AC2 7) chain B residue 67 type sequence K description BINDING SITE FOR RESIDUE GOL A 1556 source : AC2 8) chain B residue 68 type sequence K description BINDING SITE FOR RESIDUE GOL A 1556 source : AC2 9) chain B residue 89 type sequence Y description BINDING SITE FOR RESIDUE GOL A 1556 source : AC2 10) chain A residue 37 type sequence K description BINDING SITE FOR RESIDUE GOL A 1557 source : AC3 11) chain A residue 688 type sequence L description BINDING SITE FOR RESIDUE GOL A 1557 source : AC3 12) chain A residue 368 type sequence I description BINDING SITE FOR RESIDUE GOL A 1558 source : AC4 13) chain B residue 63 type sequence S description BINDING SITE FOR RESIDUE GOL A 1558 source : AC4 14) chain B residue 64 type sequence G description BINDING SITE FOR RESIDUE GOL A 1558 source : AC4 15) chain B residue 26 type sequence R description BINDING SITE FOR RESIDUE GOL B 1559 source : AC5 16) chain B residue 32 type sequence Q description BINDING SITE FOR RESIDUE GOL B 1559 source : AC5 17) chain A residue 420 type sequence H description BINDING SITE FOR RESIDUE GOL A 1560 source : AC6 18) chain B residue 77 type sequence K description BINDING SITE FOR RESIDUE GOL B 1561 source : AC7 19) chain B residue 78 type sequence K description BINDING SITE FOR RESIDUE GOL B 1561 source : AC7 20) chain B residue 79 type sequence T description BINDING SITE FOR RESIDUE GOL B 1561 source : AC7 21) chain B residue 20 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:12374755, ECO:0000269|PubMed:12434151 source Swiss-Prot : SWS_FT_FI1 22) chain B residue 43 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:12374755, ECO:0000269|PubMed:12434151 source Swiss-Prot : SWS_FT_FI1 23) chain B residue 18 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:17525332 source Swiss-Prot : SWS_FT_FI5 24) chain A residue 698 type MOD_RES sequence K description Phosphoserine => ECO:0007744|PubMed:17525332 source Swiss-Prot : SWS_FT_FI5 25) chain B residue 112 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 26) chain B residue 123 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 27) chain B residue 13 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI4

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