eF-site ID 1n49-D PDB Code 1n49 Chain D click to enlarge Title Viability of a Drug-Resistant HIV-1 Protease Variant: Structural Insights for Better Anti-Viral Therapy Classification HYDROLASE/HYDROLASE INHIBITOR Compound Protease Source null (POL_HV1A2) Sequence D:  PQITLWKRPLVTIRIGGQLKEALLNTGADDTVLEEMNLPG KWKPKMIGGIGGFIKVRQYDQIPVEICGHKAIGTVLVGPT PANIIGRNLLTQIGCTLNF Description Functional site 1) chain D residue 25 type sequence N description BINDING SITE FOR RESIDUE RIT D 401 source : AC2 2) chain D residue 27 type sequence G description BINDING SITE FOR RESIDUE RIT D 401 source : AC2 3) chain D residue 28 type sequence A description BINDING SITE FOR RESIDUE RIT D 401 source : AC2 4) chain D residue 29 type sequence D description BINDING SITE FOR RESIDUE RIT D 401 source : AC2 5) chain D residue 48 type sequence G description BINDING SITE FOR RESIDUE RIT D 401 source : AC2 6) chain D residue 49 type sequence G description BINDING SITE FOR RESIDUE RIT D 401 source : AC2 7) chain D residue 50 type sequence I description BINDING SITE FOR RESIDUE RIT D 401 source : AC2 8) chain D residue 81 type sequence P description BINDING SITE FOR RESIDUE RIT D 401 source : AC2 9) chain D residue 84 type sequence I description BINDING SITE FOR RESIDUE RIT D 401 source : AC2 10) chain D residue 78 type SITE sequence G description Cleavage; by viral protease => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 11) chain D residue 78 type MOD_RES sequence G description Phosphotyrosine; by host => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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