eF-site ID 1mwh-A PDB Code 1mwh Chain A click to enlarge Title REOVIRUS POLYMERASE LAMBDA3 BOUND TO MRNA CAP ANALOG Classification VIRAL PROTEIN Compound MINOR CORE PROTEIN LAMBDA 3 Source null (VL3_REOVD) Sequence A:  SSMILTQFGPFIESISGITDQSNDVFEDAAKAFSMFTRSD VYKALDEIPFSDDAMLPIPPTIYTKPSHDSYYYIDALNRV RRKTYQGPDDVYVPNCSIVELLEPHETLTSYGRLSEAIEN RAKDGDSQARIATTYGRIAESQARQIKAPLEKFVLALLVA EAGGSLYDPVLQKYDEIPDLSHNCPLWCFREICRHISGPL PDRAPYLYLSAGVFWLMSPRMTSAIPPLLSDLVNLAILQQ TAGLDPSLVKLGVQICLHAAASSSYSWFILKTKSIFPQNT LHSMYESLEGGYCPNLEWLEPRSDYKFMYMGVMPLSAKYA RSAPSNDKKARELGEKYGLSSVVGELRKRTKTYVKHDFAS VRYIRDAMACTSGIFLVRTPTETVLQEYTQSPEIKVPIPQ KDWTGPIGEIRILKDTTSSIARYLYRTWYLAAARMAAQPR TWDPLFQAIMRSQYVTARGGSGAALRESLYAINVSLPDFK GLPVKAATKIFQAAQLANLPFSHTSVAILADTSMGLRNQV QRRPRSIMPLNVPQQQVSAPHTLTADYINYHMNLSPTSGS AVIEKVIPLGVYASSPPNQSINIDISACDASITWDFFLSV IMAAIHEGVASSSIGKPFMGVPASIVNDESVVGVRAARPI SGMQNMIQHLSKLYKRGFSYRVNDSFSPGNDFTHMTTTFP SGSTATSTEHTANNSTMMETFLTVWGPEHTDDPDVLRLMK SLTIQRNYVCQGDDGLMIIDGTTAGKVNSETIQNDLELIS KYGEEFGWKYDIAYDGTAEYLKLYFIFGCRIPNLSRHPIV GKERANSSAEEPWPAILDQIMGVFFNGVHDGLQWQRWIRY SWALCCAFSRQRTMIGESVGYLQYPMWSFVYWGLPLVKAF GSDPWIFSWYMPTGDLGMYSWISLIRPLMTRWMVANGYVT DRCSTVFGNADYRRCFNELKLYQGYYMAQLPRNPKEVREQ FTQALSDYLMQNPELKSRVLRGRSEWEKYGAGIIHNPPSL FDVPHKWYQGAQEAAIATREELAEMDETLMRARRHSYSSF SKLLEAYLLVKWRMCEAREPSVDLRLPLCAGIDPLNSDPF LKMVSVGPMLQSTRKYFAQTLFMAKTVSGLDVNAIDSALL RLRTLGADKKALTAQLLMVGLQESEADALAGKIMLQDVNT VQLARVVNLAVPDTWMSLDFDSMFKHHVKLLPKDGRHLNT DIPPRMGWLRAILRFLGAGMVMTATGVAVDIYLEDIHGGG RSLGQRFMTWMRQEGR Description Functional site 1) chain A residue 585 type sequence D description BINDING SITE FOR RESIDUE MN A 1500 source : AC1 2) chain A residue 735 type sequence D description BINDING SITE FOR RESIDUE MN A 1500 source : AC1 3) chain A residue 780 type sequence E description BINDING SITE FOR RESIDUE MN A 1500 source : AC1 4) chain A residue 35 type sequence S description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 5) chain A residue 36 type sequence M description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 6) chain A residue 211 type sequence S description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 7) chain A residue 811 type sequence E description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 8) chain A residue 813 type sequence P description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 9) chain A residue 814 type sequence W description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 10) chain A residue 851 type sequence R description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 11) chain A residue 852 type sequence Q description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 12) chain A residue 853 type sequence R description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 13) chain A residue 854 type sequence T description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 14) chain A residue 855 type sequence M description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 15) chain A residue 862 type sequence Y description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 16) chain A residue 1031 type sequence L description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2 17) chain A residue 1035 type sequence D description BINDING SITE FOR RESIDUE GTG A 1425 source : AC2

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