eF-site ID 1mv5-ABCD PDB Code 1mv5 Chain A, B, C, D click to enlarge Title Crystal structure of LmrA ATP-binding domain Classification TRANSPORT PROTEIN Compound Multidrug resistance ABC transporter ATP-binding and permease protein Source (LMRA_LACLA) Sequence A:  MLSARHVDFAYDDSEQILRDISFEAQPNSIIAFAGPSGGG KSTIFSLLERFYQPTAGEITIDGQPIDNISLENWRSQIGF VSQDSAIMAGTIRENLTYGLEGDYTDEDLWQVLDLAFARS FVENMPDQLNTEVGERGVKISGGQRQRLAIARAFLRNPKI LMLDEATASLDSESESMVQKALDSLMKGRTTLVIAHRLST IVDADKIYFIEKGQITGSGKHNELVATHPLYAKYVSEQLT VG B:  MLSARHVDFAYDDSEQILRDISFEAQPNSIIAFAGPSGGG KSTIFSLLERFYQPTAGEITIDGQPIDNISLENWRSQIGF VSQDSAIMAGTIRENLTYGLEGDYTDEDLWQVLDLAFARS FVENMPDQLNTEVGERGVKISGGQRQRLAIARAFLRNPKI LMLDEATASLDSESESMVQKALDSLMKGRTTLVIAHRLST IVDADKIYFIEKGQITGSGKHNELVATHPLYAKYVSEQLT VG C:  MLSARHVDFAYDDSEQILRDISFEAQPNSIIAFAGPSGGG KSTIFSLLERFYQPTAGEITIDGQPIDNISLENWRSQIGF VSQDSAIMAGTIRENLTYGLEGDYTDEDLWQVLDLAFARS FVENMPDQLNTEVGERGVKISGGQRQRLAIARAFLRNPKI LMLDEATASLDSESESMVQKALDSLMKGRTTLVIAHRLST IVDADKIYFIEKGQITGSGKHNELVATHPLYAKYVSEQLT VG D:  MLSARHVDFAYDDSEQILRDISFEAQPNSIIAFAGPSGGG KSTIFSLLERFYQPTAGEITIDGQPIDNISLENWRSQIGF VSQDSAIMAGTIRENLTYGLEGDYTDEDLWQVLDLAFARS FVENMPDQLNTEVGERGVKISGGQRQRLAIARAFLRNPKI LMLDEATASLDSESESMVQKALDSLMKGRTTLVIAHRLST IVDADKIYFIEKGQITGSGKHNELVATHPLYAKYVSEQLT V Description Functional site 1) chain C residue 2353 type sequence D description BINDING SITE FOR RESIDUE MG C 1601 source : AC1 2) chain D residue 3383 type sequence S description BINDING SITE FOR RESIDUE MG D 3601 source : AC2 3) chain A residue 352 type sequence Y description BINDING SITE FOR RESIDUE ATP A 601 source : AC3 4) chain A residue 353 type sequence D description BINDING SITE FOR RESIDUE ATP A 601 source : AC3 5) chain A residue 356 type sequence E description BINDING SITE FOR RESIDUE ATP A 601 source : AC3 6) chain A residue 358 type sequence I description BINDING SITE FOR RESIDUE ATP A 601 source : AC3 7) chain A residue 379 type sequence G description BINDING SITE FOR RESIDUE ATP A 601 source : AC3 8) chain A residue 380 type sequence G description BINDING SITE FOR RESIDUE ATP A 601 source : AC3 9) chain A residue 381 type sequence G description BINDING SITE FOR RESIDUE ATP A 601 source : AC3 10) chain A residue 382 type sequence K description BINDING SITE FOR RESIDUE ATP A 601 source : AC3 11) chain A residue 383 type sequence S description BINDING SITE FOR RESIDUE ATP A 601 source : AC3 12) chain A residue 384 type sequence T description BINDING SITE FOR RESIDUE ATP A 601 source : AC3 13) chain D residue 3355 type sequence S description BINDING SITE FOR RESIDUE ATP A 601 source : AC3 14) chain D residue 3356 type sequence E description BINDING SITE FOR RESIDUE ATP A 601 source : AC3 15) chain B residue 1352 type sequence Y description BINDING SITE FOR RESIDUE ADP B 1600 source : AC4 16) chain B residue 1356 type sequence E description BINDING SITE FOR RESIDUE ADP B 1600 source : AC4 17) chain B residue 1358 type sequence I description BINDING SITE FOR RESIDUE ADP B 1600 source : AC4 18) chain B residue 1378 type sequence S description BINDING SITE FOR RESIDUE ADP B 1600 source : AC4 19) chain B residue 1379 type sequence G description BINDING SITE FOR RESIDUE ADP B 1600 source : AC4 20) chain B residue 1380 type sequence G description BINDING SITE FOR RESIDUE ADP B 1600 source : AC4 21) chain B residue 1381 type sequence G description BINDING SITE FOR RESIDUE ADP B 1600 source : AC4 22) chain B residue 1382 type sequence K description BINDING SITE FOR RESIDUE ADP B 1600 source : AC4 23) chain B residue 1383 type sequence S description BINDING SITE FOR RESIDUE ADP B 1600 source : AC4 24) chain B residue 1384 type sequence T description BINDING SITE FOR RESIDUE ADP B 1600 source : AC4 25) chain C residue 2353 type sequence D description BINDING SITE FOR RESIDUE ADP B 1600 source : AC4 26) chain C residue 2355 type sequence S description BINDING SITE FOR RESIDUE ADP B 1600 source : AC4 27) chain B residue 1353 type sequence D description BINDING SITE FOR RESIDUE ATP C 2601 source : AC5 28) chain B residue 1355 type sequence S description BINDING SITE FOR RESIDUE ATP C 2601 source : AC5 29) chain B residue 1356 type sequence E description BINDING SITE FOR RESIDUE ATP C 2601 source : AC5 30) chain C residue 2352 type sequence Y description BINDING SITE FOR RESIDUE ATP C 2601 source : AC5 31) chain C residue 2378 type sequence S description BINDING SITE FOR RESIDUE ATP C 2601 source : AC5 32) chain C residue 2379 type sequence G description BINDING SITE FOR RESIDUE ATP C 2601 source : AC5 33) chain C residue 2380 type sequence G description BINDING SITE FOR RESIDUE ATP C 2601 source : AC5 34) chain C residue 2381 type sequence G description BINDING SITE FOR RESIDUE ATP C 2601 source : AC5 35) chain C residue 2382 type sequence K description BINDING SITE FOR RESIDUE ATP C 2601 source : AC5 36) chain C residue 2383 type sequence S description BINDING SITE FOR RESIDUE ATP C 2601 source : AC5 37) chain C residue 2384 type sequence T description BINDING SITE FOR RESIDUE ATP C 2601 source : AC5 38) chain A residue 353 type sequence D description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 39) chain A residue 355 type sequence S description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 40) chain D residue 3352 type sequence Y description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 41) chain D residue 3356 type sequence E description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 42) chain D residue 3358 type sequence I description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 43) chain D residue 3377 type sequence P description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 44) chain D residue 3378 type sequence S description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 45) chain D residue 3379 type sequence G description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 46) chain D residue 3380 type sequence G description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 47) chain D residue 3381 type sequence G description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 48) chain D residue 3382 type sequence K description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 49) chain D residue 3383 type sequence S description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 50) chain D residue 3384 type sequence T description BINDING SITE FOR RESIDUE ADP D 3600 source : AC6 51) chain A residue 481-495 type prosite sequence ISGGQRQRLAIARAF description ABC_TRANSPORTER_1 ABC transporters family signature. ISGGQRQRLAIARAF source prosite : PS00211 52) chain A residue 382 type BINDING sequence K description BINDING => ECO:0000255|PROSITE-ProRule:PRU00434 source Swiss-Prot : SWS_FT_FI1 53) chain B residue 1382 type BINDING sequence K description BINDING => ECO:0000255|PROSITE-ProRule:PRU00434 source Swiss-Prot : SWS_FT_FI1 54) chain C residue 2382 type BINDING sequence K description BINDING => ECO:0000255|PROSITE-ProRule:PRU00434 source Swiss-Prot : SWS_FT_FI1 55) chain D residue 3382 type BINDING sequence K description BINDING => ECO:0000255|PROSITE-ProRule:PRU00434 source Swiss-Prot : SWS_FT_FI1

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