eF-site ID 1muf-A PDB Code 1muf Chain A click to enlarge Title Structure of histone H3 K4-specific methyltransferase SET7/9 Classification TRANSFERASE Compound SET9 Source Homo sapiens (Human) (SET7_HUMAN) Sequence A:  VLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCW IYYPDGGSLVGEVNEDGEXTGEKIAYVYPDERTALYGKFI DGEXIEGKLATLXSTEEGRPHFELXPGNSVYHFDKSTSSC ISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNT VXSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEP YNHVSKYCASLGHKANHSFTPNCIYDXFVHPRFGPIKCIR TLRAVEADEELTVAYGY Description (1)  SET9 (2.1.1.43) Functional site 1) chain A residue 245 type catalytic sequence Y description 350 source MCSA : MCSA1 2) chain A residue 293 type catalytic sequence H description 350 source MCSA : MCSA1 3) chain A residue 297 type catalytic sequence H description 350 source MCSA : MCSA1 4) chain A residue 305 type catalytic sequence Y description 350 source MCSA : MCSA1 5) chain A residue 335 type catalytic sequence Y description 350 source MCSA : MCSA1 6) chain A residue 226 type BINDING sequence A description BINDING => ECO:0000269|PubMed:12514135, ECO:0000269|PubMed:12540855 source Swiss-Prot : SWS_FT_FI1 7) chain A residue 296 type BINDING sequence N description BINDING => ECO:0000269|PubMed:12514135, ECO:0000269|PubMed:12540855 source Swiss-Prot : SWS_FT_FI1 8) chain A residue 297 type BINDING sequence H description BINDING => ECO:0000269|PubMed:12514135, ECO:0000269|PubMed:12540855 source Swiss-Prot : SWS_FT_FI1 9) chain A residue 245 type SITE sequence Y description Histone H3K4 binding => ECO:0000269|PubMed:12540855 source Swiss-Prot : SWS_FT_FI2 10) chain A residue 256 type SITE sequence D description Histone H3K4 binding => ECO:0000269|PubMed:12540855 source Swiss-Prot : SWS_FT_FI2 11) chain A residue 266 type SITE sequence T description Histone H3K4 binding => ECO:0000269|PubMed:12540855 source Swiss-Prot : SWS_FT_FI2 12) chain A residue 317 type SITE sequence K description Histone H3K4 binding => ECO:0000269|PubMed:12540855 source Swiss-Prot : SWS_FT_FI2 13) chain A residue 335 type SITE sequence Y description Histone H3K4 binding => ECO:0000269|PubMed:12540855 source Swiss-Prot : SWS_FT_FI2

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