|
|
eF-site ID
|
1msb-B |
|
PDB Code
|
1msb |
|
Chain
|
B |
|
click to enlarge
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Title
|
STRUCTURE OF THE CALCIUM-DEPENDENT LECTIN DOMAIN FROM A RAT MANNOSE-BINDING PROTEIN DETERMINED BY MAD PHASING |
|
Classification
|
HEPATIC LECTIN |
|
Compound
|
MANNOSE-BINDING PROTEIN-A |
|
Source
|
Rattus norvegicus (Rat) (MBL1_RAT) |
|
|
Sequence
|
B: |
SGKKFFVTNHERMPFSKVKALCSELRGTVAIPRNAEENKA
IQEVAKTSAFLGITDEVTEGQFMYVTGGRLTYSNWKKDEP
NDHGSGEDCVTIVDNGLWNDISCQASHTAVCEFPA
|
|
|
Description
|
(1) |
MANNOSE BINDING PROTEIN A (LECTIN DOMAIN) COMPLEX WITH HOLMIUM
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
161 |
| type |
|
| sequence |
D
|
| description |
|
| source |
: HO3
|
|
|
2)
|
chain |
B |
| residue |
165 |
| type |
|
| sequence |
E
|
| description |
|
| source |
: HO3
|
|
|
3)
|
chain |
B |
| residue |
188 |
| type |
|
| sequence |
D
|
| description |
|
| source |
: HO3
|
|
|
4)
|
chain |
B |
| residue |
193 |
| type |
|
| sequence |
E
|
| description |
|
| source |
: HO3
|
|
|
5)
|
chain |
B |
| residue |
194 |
| type |
|
| sequence |
D
|
| description |
|
| source |
: HO3
|
|
|
6)
|
chain |
B |
| residue |
185 |
| type |
|
| sequence |
E
|
| description |
|
| source |
: HO4
|
|
|
7)
|
chain |
B |
| residue |
187 |
| type |
|
| sequence |
N
|
| description |
|
| source |
: HO4
|
|
|
8)
|
chain |
B |
| residue |
193 |
| type |
|
| sequence |
E
|
| description |
|
| source |
: HO4
|
|
|
9)
|
chain |
B |
| residue |
205 |
| type |
|
| sequence |
N
|
| description |
|
| source |
: HO4
|
|
|
10)
|
chain |
B |
| residue |
206 |
| type |
|
| sequence |
D
|
| description |
|
| source |
: HO4
|
|
|
11)
|
chain |
B |
| residue |
161 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE HO B 1
|
| source |
: AC3
|
|
|
12)
|
chain |
B |
| residue |
165 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE HO B 1
|
| source |
: AC3
|
|
|
13)
|
chain |
B |
| residue |
188 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE HO B 1
|
| source |
: AC3
|
|
|
14)
|
chain |
B |
| residue |
193 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE HO B 1
|
| source |
: AC3
|
|
|
15)
|
chain |
B |
| residue |
194 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE HO B 1
|
| source |
: AC3
|
|
|
16)
|
chain |
B |
| residue |
185 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE HO B 2
|
| source |
: AC4
|
|
|
17)
|
chain |
B |
| residue |
187 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE HO B 2
|
| source |
: AC4
|
|
|
18)
|
chain |
B |
| residue |
193 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE HO B 2
|
| source |
: AC4
|
|
|
19)
|
chain |
B |
| residue |
205 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE HO B 2
|
| source |
: AC4
|
|
|
20)
|
chain |
B |
| residue |
206 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE HO B 2
|
| source |
: AC4
|
|
|
21)
|
chain |
B |
| residue |
161 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1AFA, ECO:0007744|PDB:1AFB, ECO:0007744|PDB:1AFD, ECO:0007744|PDB:1BCH, ECO:0007744|PDB:1BCJ, ECO:0007744|PDB:1FIF, ECO:0007744|PDB:1FIH, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
22)
|
chain |
B |
| residue |
165 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1AFA, ECO:0007744|PDB:1AFB, ECO:0007744|PDB:1AFD, ECO:0007744|PDB:1BCH, ECO:0007744|PDB:1BCJ, ECO:0007744|PDB:1FIF, ECO:0007744|PDB:1FIH, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
23)
|
chain |
B |
| residue |
188 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1AFA, ECO:0007744|PDB:1AFB, ECO:0007744|PDB:1AFD, ECO:0007744|PDB:1BCH, ECO:0007744|PDB:1BCJ, ECO:0007744|PDB:1FIF, ECO:0007744|PDB:1FIH, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
24)
|
chain |
B |
| residue |
194 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1AFA, ECO:0007744|PDB:1AFB, ECO:0007744|PDB:1AFD, ECO:0007744|PDB:1BCH, ECO:0007744|PDB:1BCJ, ECO:0007744|PDB:1FIF, ECO:0007744|PDB:1FIH, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
25)
|
chain |
B |
| residue |
206 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
26)
|
chain |
B |
| residue |
185 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
27)
|
chain |
B |
| residue |
187 |
| type |
BINDING |
| sequence |
N
|
| description |
BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
28)
|
chain |
B |
| residue |
193 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
29)
|
chain |
B |
| residue |
205 |
| type |
BINDING |
| sequence |
N
|
| description |
BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|